An observational study in Gestational Diabetes, Hyperglycemia and Insulin Resistance, sponsored by Anthony Hanley. Completed at 1 site in Canada. Open to female participants aged 20 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-11-28.
Sponsored by Anthony Hanley · Observational
Childhood obesity is on the rise and is a major risk factor for type 2 diabetes later in life. Recent evidence indicates that abnormalities that increase risk for diabetes may be initiated early in infancy. Since the offspring of women with diabetes have an increased long-term risk for obesity and type 2 diabetes, the impact of maternal metabolic abnormalities on early nutrition and infant metabolic trajectories is of considerable interest. The purpose of the study is to investigate the impact of maternal nutrition and metabolic abnormalities in pregnancy on human milk and subsequently on infant health over the first year of life.
The current investigation is a prospective study conducted within ongoing cohort studies of women and their offspring. Pregnant women attending outpatient obstetrics clinics in Toronto, Canada are recruited. The overall study protocol includes four study visits between the second half of pregnancy and the first year of infant's life and interim phone call interviews:
842 studies on the registry are indexed under Diabetes, Gestational; 199 are open to participants now.
This study's enrollment of 271 is above the median of 198 across 270 observational studies indexed under Diabetes, Gestational.
Browse Diabetes, Gestational studies →This is the only study on the registry with Anthony Hanley as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Pregnant women are recruited in outpatient clinic waiting areas at Mount Sinai Hospital in Toronto, Canada, a large tertiary care centre.
Exclusion Criteria:
Infant growth
Time frame: Growth from birth to anthrometry at 12mo
Human milk composition
Time frame: At 3d and at 3mo postpartum
Onset of lactogenesis II
If the participant reports no milk-coming-in at the day 7 postpartum interview, the response is recorded as no milk-coming-in by day 7 postpartum.
Time frame: At 3d, 5d, 7d postpartum until the event occurrence of milk-coming-in up to day 7.
Gestational diabetes
Time frame: An expected average of 30 weeks of gestation
Gestational metabolic abnormalities
Time frame: An expected average of 30 weeks of gestation
Getational hyperglycemia and insulinemia (insulin resistance/sensitivity)
Time frame: An expected average of 30 weeks of gestation
This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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