An interventional study of Ferrous sulfate and Ferrous sulfate in Iron Deficiency, sponsored by Swiss Federal Institute of Technology. Completed at 1 site in Switzerland. Open to female participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-01-06.
Sponsored by Swiss Federal Institute of Technology · Not applicable, Interventional, and Basic science
The overall goal of this research is to develop safe and effective iron interventions that can be administered without production of plasma non-transferrin-bound iron (NTBI: iron in the systemic circulation not bound to the iron-transport protein transferrin). The appearance of plasma non-transferrin-bound iron has been reported in uninfected adult volunteers after oral administration of iron supplements in doses similar to those used in the Pemba trial. This research project will (i) confirm the appearance of plasma non-transferrin-bound iron after administration of an iron supplement like that in the Pemba trial (\~1 mg Fe/kg body weight, without food), and then determine the effects on production of plasma non-transferrin-bound iron and on iron absorption measured with stable isotopes (ii) of giving the supplemental iron (\~1 mg Fe/kg) with the standard rice meal, and (iii) of giving a lower dose of iron (\~0.1 mg Fe/kg) - like that used in home fortification - with the standard rice meal.
772 studies on the registry are indexed under Iron Deficiencies; 115 are open to participants now.
This study's enrollment of 32 is below the median of 100 across 592 interventional studies indexed under Iron Deficiencies.
Browse Iron Deficiencies studies →Swiss Federal Institute of Technology is the lead sponsor of 152 studies on the registry; 10 are open to participants now.
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Exclusion Criteria:
Dietary Supplement: Ferrous sulfate
Dietary Supplement: Ferrous sulfate
Dietary Supplement: Ferrous sulfate
60 mg Ferrous sulfate
60 mg ferrous sulfate
6 mg ferrous sulfate
Formation of NTBI following oral iron administration
Time frame: 6 time points within 8 hours
Serum iron isotope appearance curves
Time frame: 6 time points within 8 hours
This study is completed, as verified in Jan 2012. You cannot join it, but the record below documents what was studied.
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Swiss Federal Institute of Technology