An interventional study of Delayed cord clamping and Milking of the cord in Premature Birth, sponsored by Medstar Health Research Institute. Terminated. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-02-22.
Sponsored by Medstar Health Research Institute · Not applicable and Interventional
This study is being done to evaluate if delaying cord clamping or milking the umbilical cord of the preterm infant has health benefits for the baby. Timing of clamping of the cord varies among doctors, but there is information that shows that delaying clamping of the umbilical cord in premature infants may reduce the rate of the baby needing a blood transfusion, decrease the risk of infection and bleeding in the head.
2,557 studies on the registry are indexed under Premature Birth; 500 are open to participants now.
This study's enrollment of 2 is below the median of 84 across 1,691 interventional studies indexed under Premature Birth.
Browse Premature Birth studies →Medstar Health Research Institute is the lead sponsor of 160 studies on the registry; 32 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 6 (43%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Delayed cord clamping for 30 seconds
Procedure: Delayed cord clamping
Milking of the cord 4 times in 10 seconds
Procedure: Milking of the cord
Immediate cord clamping after delivery
Delay cord clamping for 30 seconds after birth
Milking of the cord 4 times in 10 seconds
Adverse Neonatal Event
composite of bronchopulmonary dysplasia (BPD), necrotising eneterocolitis (NEC), grade 3 or 4 intraventricular hemorrhage (IVH) or periventricular leukomalacia (PVL), or death prior to discharge home
Time frame: up to 24 weeks after birth
Maternal estimated blood loss
Estimated blood loss at delivery
Time frame: up to 1 hour after delivery
Any grade intraventricular hemorrhage
Time frame: up to 24 weeks after birth
Severe intraventricular hemorrhage (grade 3 or 4)
Time frame: up to 24 weeks after birth
Periventricular leukomalacia
Time frame: up to 24 weeks after birth
Bronchopulmonary dysplasia
Time frame: up to 24 weeks after birth
Peak transcutaneous and/or serum bilirubin concentrations
Time frame: up to 24 weeks after birth
Phototherapy
Requirement and length of phototherapy
Time frame: up to 24 weeks after birth
Ionotropic support
Requirement and length of ionotropic support
Time frame: up to 24 weeks after birth
Neonatal intesive care unit (NICU) length of stay
Time frame: up to 24 weeks after birth
Sepsis
Time frame: up to 24 weeks after birth
Necrotizing enterocolitis
Time frame: up to 24 weeks after birth
Respiratory distress syndrome
Time frame: up to 24 weeks after birth
Number of blood transfusions while in the neonatal intensive care unit
Time frame: up to 24 weeks after birth
Ventilator time
Time frame: up to 24 weeks after birth
Apgar score <7 at 5 minutes
Time frame: at 5 minutes after birth
Umbilical cord pH < 7.0
Time frame: up to 30 minutes after birth
Blood pressure on admission to neonatal intensive care unit
Time frame: at 30 minutes after birth
Polycythemia
Time frame: up to 24 hours of life
Hematocrit on admission to neonatal intensive care unit
Time frame: up to 4 hours after birth
Neonatal death
Time frame: up to 24 weeks of life
Length of 3rd stage of labor
Time period between delivery of the baby and delivery of the placenta
Time frame: up to 1 hour after birth
Use of uterotonic agents
Time frame: up to 1 hour after birth
Maternal blood transfusion
Time frame: up to 5 days after delivery
Manual removal of placenta
Time frame: up to 1 hour after birth
Operating time for cesarean delivery
Time frame: up to 3 hours after birth
No study locations are listed for this record.
This study is terminated, as verified in Feb 2013. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Medstar Health Research Institute