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CompletedNCT01380925Updated May 11, 2016

The Jewels in Our Genes Study - an African American Family Study of Breast Cancer

An observational study in Breast Cancer, sponsored by University at Buffalo. Completed at 1 site in United States. Open to female participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2016-05-11.

Sponsored by University at Buffalo · Observational

Study type
Observational
Model
Family-based
Time perspective
Cross-sectional
Enrollment
330
Ages
18 Years to 100 Years
Sex
Female
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Study summary

The research team is studying why some African American families have multiple cases of breast cancer.

This study will help to better understand if there are undiscovered genes unique to African Americans that may predict early breast cancer risk.

Breast cancer survivors AND their relatives who are also breast cancer survivors are being recruited to the study.

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Conditions studied

  • Breast Cancer

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In context

Breast Neoplasms

12,544 studies on the registry are indexed under Breast Neoplasms; 2,892 are open to participants now.

This study's enrollment of 330 is above the median of 184 across 2,642 observational studies indexed under Breast Neoplasms.

Browse Breast Neoplasms studies →

Lead sponsor

University at Buffalo is the lead sponsor of 73 studies on the registry; none are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 5 (83%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

African American breast cancer survivors.

Inclusion criteria

  • Black/African American
  • Ever diagnosed with breast cancer
  • Have at least one living blood relative ever diagnosed with breast cancer, who is also willing to participate
  • Live in the U.S.

Exclusion criteria

Exclusion Criteria:

  • Tested positive for BRCA mutations
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Study design

Observational model
Family-based
Time perspective
Cross-sectional
Enrollment
330 participants (actual)
Biospecimen retention
Samples with dna
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What researchers measure

Primary outcomes

  1. breast cancer

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Study locations

1 site
  • University at Buffalo
    Buffalo, New York 14214-8001, United States
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References and documents

Publications

  • Ochs-Balcom HM, Sun X, Chen Y, Barnholtz-Sloan J, Erwin DO, Jandorf L, Sucheston-Campbell L, Elston RC. Putative linkage signals identified for breast cancer in African American families. Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):442-7. doi: 10.1158/1055-9965.EPI-14-1131. Epub 2014 Dec 4. PubMed 25477366 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01380925
Lead sponsor
University at Buffalo
Collaborators
Susan G. Komen Breast Cancer Foundation
Responsible party
Heather Ochs-Balcom (Assistant Professor, University at Buffalo) — Principal investigator
First posted
Jun 27, 2011
Start date
Oct 2010
Primary completion
Aug 2012
Completion
Aug 2012
Last update
May 11, 2016

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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