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CompletedNCT01376843Updated Mar 6, 2013

Conversion Rate of (TST) Tuberculin Skin Test and Quantiferon-TB Gold In Tube Assay in Health Care Workers

An observational study in Tuberculosis, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 75 Years. Per ClinicalTrials.gov, last updated 2013-03-06.

Sponsored by Yonsei University · Observational

Study type
Observational
Model
Case-crossover
Time perspective
Prospective
Enrollment
53
Ages
20 Years to 75 Years
Sex
All
01

Study summary

The purpose of this study is to access conversion rate of TST (Tuberculin skin test) and Quantiferon-TB Gold In tube assay in health care workers.

02

Conditions studied

  • Tuberculosis

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Keywords

  • latent tuberculosis in health care workers
03

In context

Tuberculosis

1,417 studies on the registry are indexed under Tuberculosis; 208 are open to participants now.

This study's enrollment of 53 is below the median of 250 across 421 observational studies indexed under Tuberculosis.

Browse Tuberculosis studies →

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

health care workers who performed TST or Quantiferon-TB Gold In tube assay before

Inclusion criteria

  • age 20-75, men and women
  • participant who was enrolled in the study of latent tuberculosis in health care worker (IRB No.4-2009-0187)
  • high risk or low risk health care worker who was performed TST or Quantiferon-TB Gold In tube assay before

Exclusion criteria

Exclusion Criteria:

  • age \< 20
  • person who don't agree with enrollment
  • illiterate
  • person who is diagnosed as active tuberculosis now
  • person who has history of hypersensitivity on PPD (tuberculin purified protein derivative)
  • pregnant woman
  • person who is treated as active tuberculosis
05

Study design

Observational model
Case-crossover
Time perspective
Prospective
Enrollment
53 participants (actual)
Biospecimen retention
Samples without dna

Groups and cohorts

  • Health care workers

    health care workers who performed TST or Quantiferon-TB Gold In tube assay before

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What researchers measure

Primary outcomes

  1. conversion rate of latent tuberculosis infection in hospital workers

    Time frame: 3months

07

Study locations

1 site
  • Severance Hospital
    Seoul, 120-752, Korea, Republic of
08

References and documents

Publications

  • Menzies D, Fanning A, Yuan L, Fitzgerald M. Tuberculosis among health care workers. N Engl J Med. 1995 Jan 12;332(2):92-8. doi: 10.1056/NEJM199501123320206. No abstract available. PubMed 7990907 ↗
  • Jiamjarasrangsi W, Hirunsuthikul N, Kamolratanakul P. Tuberculosis among health care workers at King Chulalongkorn Memorial Hospital, 1988-2002. Int J Tuberc Lung Dis. 2005 Nov;9(11):1253-8. PubMed 16333934 ↗
  • Schwartzman K, Loo V, Pasztor J, Menzies D. Tuberculosis infection among health care workers in Montreal. Am J Respir Crit Care Med. 1996 Oct;154(4 Pt 1):1006-12. doi: 10.1164/ajrccm.154.4.8887599. PubMed 8887599 ↗
  • Kruuner A, Danilovitsh M, Pehme L, Laisaar T, Hoffner SE, Katila ML. Tuberculosis as an occupational hazard for health care workers in Estonia. Int J Tuberc Lung Dis. 2001 Feb;5(2):170-6. PubMed 11258511 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 6, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01376843
Lead sponsor
Yonsei University
Responsible party
Sponsor
First posted
Jun 20, 2011
Start date
Jun 2011
Primary completion
May 2012
Completion
May 2012
Last update
Mar 6, 2013

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2013. You cannot join it, but the record below documents what was studied.

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