CClinicalTrials.gg
Status unknownNCT01355185Updated Oct 3, 2014

Seed Movement in Prostate Brachytherapy Implants: Clinical Measurement and Dosimetric Consequences

An observational study in Prostate Cancer, sponsored by AHS Cancer Control Alberta. Status unknown at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2014-10-03.

Sponsored by AHS Cancer Control Alberta · Observational

The sponsor has not verified this record recently (last verified Oct 2014), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
20
Ages
18 Years and older
Sex
All
01

Study summary

There are substantial uncertainties with contemporary seed placement techniques in prostate brachytherapy, particularly with the impact of seed movement after an implant due to edema and migration of seeds in the prostate and peri-prostatic tissues. This study will accrue 20 patients undergoing prostate brachytherapy implants and perform serial CT and MRI scans at specified intervals (pre-operatively, day 0, day 3, day 10 and day 28) to characterize these phenomena.

Read the detailed description

Prostate brachytherapy is an effective treatment option for men with localized prostate cancer with excellent cure rates and a favorable toxicity profile. Having a more detailed understanding of seed movement after an implant will provide clinicians with details about the clinical impact of these phenomena on implants and provide the detailed understanding of these phenomena that are necessary for more sophisticated brachytherapy implants that are envisioned in the future.

02

Conditions studied

  • Prostate Cancer

Browse trials for

Keywords

  • Seed movement
  • implants
  • prostate brachytherapy
  • localized
03

In context

Prostatic Neoplasms

6,367 studies on the registry are indexed under Prostatic Neoplasms; 1,397 are open to participants now.

This study's planned enrollment of 20 is below the median of 200 across 1,179 observational studies indexed under Prostatic Neoplasms.

Browse Prostatic Neoplasms studies →

Lead sponsor

AHS Cancer Control Alberta is the lead sponsor of 182 studies on the registry; 31 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients seen at an academic institution (tertiary centre ...Cross Cancer Institute) for consideration of prostate brachytherapy

Inclusion criteria

  • treated with prostate brachytherapy
  • low risk or intermediate risk prostate cancer
  • ambulatory
  • stable medical condition
  • 18 years of age or older
  • capable of informed consent

Exclusion criteria

Exclusion Criteria:

  • no use of any hormonal therapy
  • unable to have MRI scans (ie. presence of metallic foreign object, aneurysm clip, cardiac pacemaker, internal wires, implanted pump, implanted cardiac device, claustrophobia, etc.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
20 participants (estimated)
06

Study locations

1 of 1 sites recruiting
07

References and documents

Publications

  • Sloboda RS, Usmani N, Pedersen J, Murtha A, Pervez N, Yee D. Time course of prostatic edema post permanent seed implant determined by magnetic resonance imaging. Brachytherapy. 2010 Oct-Dec;9(4):354-61. doi: 10.1016/j.brachy.2009.09.008. Epub 2010 Jan 29. PubMed 20116344 ↗
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 3, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01355185
Lead sponsor
AHS Cancer Control Alberta
Collaborators
Canadian Association of Radiation Oncology, Sanofi
Responsible party
Sponsor
First posted
May 18, 2011
Start date
Aug 2011
Primary completion
Jun 2015 (estimated)
Completion
Jun 2015 (estimated)
Last update
Oct 3, 2014

Study contacts

Nawaid Usmani, MD, FRCPC
Contact
Nawaid.Usmani@albertahealthservices.ca
780-432-8518
Ronald Sloboda, PhD
Contact
Ron.Sloboda@albertahealthservices.ca
780-432-8719
Nawaid Usmani, MD, FRCPC
principal investigator · University of Alberta
Ronald Sloboda, PhD
principal investigator · University of Alberta

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2014. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion