An observational study in HIV Infections, sponsored by Ottawa Hospital Research Institute. Completed at 1 site in Canada. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-04-29.
Sponsored by Ottawa Hospital Research Institute · Observational
The purpose of this study is to determine if the Oragene.RNA kit is able to detect HIV RNA in saliva.
There is an important need for a rapid, non-invasive, sensitive and specific method for detection of HIV RNA, particularly in clinical settings in which patients at risk for HIV exposure are assessed and screened. A rapid and non-invasive method for quantitative testing of HIV RNA would be also valuable to monitor suppression of HIV RNA as a primary surrogate marker of combination antiretroviral therapy efficacy. An Ottawa-based biotech company (DNA Genotek Inc) has developed and sells to research and clinical labs world-wide a kit (Oragene� DNA Self-collection kit) that permits the collection, stabilization at room temperature, and purification of DNA present in saliva. They have recently developed a kit (Oragene��RNA) that is purported to stabilize RNA in saliva, a non-invasive source of a biological fluid.
4,258 studies on the registry are indexed under HIV Infections; 240 are open to participants now.
This study's enrollment of 40 is below the median of 200 across 713 observational studies indexed under HIV Infections.
Browse HIV Infections studies →Ottawa Hospital Research Institute is the lead sponsor of 538 studies on the registry; 100 are open to participants now.
Counted across the registry records on this site, refreshed daily.
HIV monoinfected HIV-HCV co-infected HIV and HCV uninfected control
Four groups of 10 patients each will be recruited:
Exclusion Criteria:
This study is completed, as verified in Oct 2008. You cannot join it, but the record below documents what was studied.
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Ottawa Hospital Research Institute