An observational study in Type II Diabetes, sponsored by University of Oulu. Completed at 1 site in Finland. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2017-11-01.
Sponsored by University of Oulu · Observational
This study will investigate the effects of gastric bypass surgery on type II diabetes. The study will recruit patients with type II diabetes having Roux-en-Y gastric bypass, patients without type II diabetes having Roux-en-Y gastric bypass, and control subjects (patients having gastroscopy, but no surgery). Targeted enrollment is 30 patients per group. Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy. Meal test with incretin measurements, and feces and blood samplings are performed before and after surgery
Hypotheses are:
Primary end points are:
9,589 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,332 are open to participants now.
This study's enrollment of 41 is below the median of 300 across 1,622 observational studies indexed under Diabetes Mellitus, Type 2.
Browse Diabetes Mellitus, Type 2 studies →University of Oulu is the lead sponsor of 141 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients are recruited from Oulu University Hospital
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Inclusion Criteria (control patients without surgery):
Exclusion Criteria:
Changes in the amounts of endocrine cells in ventricle, duodenum and jejunum
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
Changes in the incretine secretion studied with liquid meal test
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
Changes in the oxidation of lipoproteins
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
Changes in the immunologic markers in ventricle, duodenum and jejunum
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
Changes in the amounts of phytosterols, cholesterol metabolites and bile acids
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
Changes in fecal microbiota
Samples of intestine are taken prior to surgery in gastroscopy, during surgery, and 6 months after surgery during gastroscopy
Time frame: baseline to 6 months
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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