A Phase 2 interventional study of Group 1 and Group 2 in Liver Failure, sponsored by Sun Yat-sen University. Status unknown. Open to participants aged 16 Years to 65 Years. Per ClinicalTrials.gov, last updated 2011-04-11.
Sponsored by Sun Yat-sen University · Phase 2, Interventional, and Treatment
Allogeneic Bone Marrow Mesenchymal Stem Cells Transplantation in Patients with Liver Failure Caused by hepatitis B virus (HBV)
445 studies on the registry are indexed under Liver Failure; 69 are open to participants now.
This study's planned enrollment of 120 is above the median of 43 across 276 interventional studies indexed under Liver Failure.
Browse Liver Failure studies →Sun Yat-sen University is the lead sponsor of 1,644 studies on the registry; 602 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Thirty of the enrolled patients were assigned to Group A to receive comprehensive treatment including antiviral drugs, lowering aminotransferase and jaundice medicine.
Other: Group 1 · Other: Group 2 · Other: Group 3
Thirty of the enrolled patients were assigned to Group B to receive comprehensive treatment, as well as allogeneic bone marrow mesenchymal stem cells transplantation by peripheral vein(2×105/Kg, once a week, 4 times).
Thirty of the enrolled patients were assigned to Group B to receive comprehensive treatment, as well as allogeneic bone marrow mesenchymal stem cells transplantation by peripheral vein(1×106/Kg, once a week, 4 times).
Thirty of the enrolled patients were assigned to Group B to receive comprehensive treatment, as well as allogeneic bone marrow mesenchymal stem cells transplantation by peripheral vein(5×106/Kg, once a week, 4 times).
Liver Function
The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase(AST),total bilirubin (TB),prothrombin time (PT), prothrombin activity(PTA),INR,albumin (ALB),globulin(GLB), prealbumin(PA),creatinine(Cr), Urea nitrogen(BUN),number of leucocyte,erythrocyte and platelet, cytokines,liver histological
Time frame: 12months
Immune state
cytokine
Time frame: 12months
No study locations are listed for this record.
This study is status unknown, as verified in Oct 2010. You cannot join it, but the record below documents what was studied.
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Sun Yat-sen University