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CompletedNCT01313468NEATUpdated Mar 30, 2017

Interval Training and Resting Metabolism

An interventional study of 1 x 4 minute interval and 4 x 4 minutes Intervals in Healthy Subjects, sponsored by Norwegian University of Science and Technology. Completed at 1 site in Norway. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-03-30.

Sponsored by Norwegian University of Science and Technology · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
Male
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Study summary

It has been reported that obese individuals are seated 2 ½ hour more than lean individuals and that non exercise thermo genesis (NEAT) may vary with as much as 2000 Kcal/day between equal size people due to different occupational and leisure time activities. The primary aim of the study is to investigate if 10 weeks of exercise training increase NEAT in sedentary men.

Subject will be randomized to three different training intervention, with 3 exercise session each week for 10 weeks. NEAT will be measured using an activity sensor and recorded over a 7 day period both before and after training.

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Conditions studied

  • Healthy Subjects

Keywords

  • NEAT
  • maximal oxygen uptake
  • stroke volume
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In context

Lead sponsor

Norwegian University of Science and Technology is the lead sponsor of 487 studies on the registry; 52 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Male gender
  • Age 18-50
  • BMI 25-30 kg x m2
  • No significant comorbidities
  • Abel to exercise
  • Not partaking in organized physical activity

Exclusion criteria

Exclusion Criteria:

  • Inability to exercise due to musculoskeletal conditions
  • Known ischemic cardiovascular disease
  • High daily physical and occupational activity levels
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    4 x 4 Interval

    4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate.

    Behavioral: 4 x 4 minutes Intervals

  • Experimental
    1 4 minutes interval

    1 x 4 minutes intervals at 90-95% of HR max

    Behavioral: 1 x 4 minute interval

  • Experimental
    Moderate continuous Training

    47 minutes of Moderate continuous Training

    Behavioral: Moderate continuous Training

Interventions

  • Behavioral1 x 4 minute interval

    1 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate

  • Behavioral4 x 4 minutes Intervals

    4 x 4 minutes of high intensity intervals at 90-95% of maximal heart rate separated by 3 minutes of active brakes in between at 70% of maximal heart rate.

  • BehavioralModerate continuous Training

    47 minutes of Moderate continuous Training

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What researchers measure

Primary outcomes

  1. nonexercise activity thermogenesis

    NEAT Will be measured using an activity sensor. Physical activity is recorded over a 7 day period. The energy equivalent of each of these activities is determined. The time spent in each activity is then multiplied by equivalent for the activity. The values are then summed to derive an estimate of NEAT.

    Time frame: Baseline and 10 weeks

Secondary outcomes

  1. Cardiopulmonary maximal oxygen uptake

    The secondary aims are to investigate the changes in maximal oxygen uptake, heart function, and body composition in response to interval training

    Time frame: Baseline and 10 weeks

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Study locations

1 site
  • NTNU
    Trondheim, 7491, Norway
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References and documents

Publications

  • Zisko N, Stensvold D, Hordnes-Slagsvold K, Rognmo O, Nauman J, Wisloff U, Karlsen T. Effect of Change in VO2max on Daily Total Energy Expenditure in a Cohort of Norwegian Men: A Randomized Pilot Study. Open Cardiovasc Med J. 2015 Apr 30;9:50-7. doi: 10.2174/1874192401509010050. eCollection 2015. PubMed 25969700 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01313468
Lead sponsor
Norwegian University of Science and Technology
Collaborators
St. Olavs Hospital
Responsible party
Sponsor
First posted
Mar 11, 2011
Start date
Feb 2011
Primary completion
Nov 2011
Completion
Nov 2011
Last update
Mar 30, 2017

Study contacts

Trine Karlsen
principal investigator · National Taiwan Normal University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2017. You cannot join it, but the record below documents what was studied.

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