An interventional study of bariatric surgery in Severely Obese Patients, sponsored by Assistance Publique Hopitaux De Marseille. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-07-24.
Sponsored by Assistance Publique Hopitaux De Marseille · Not applicable and Interventional
Growing evidence suggests that bariatric surgery is a relevant treatment for severely obese patients, especially those with metabolic complications, as it significantly reduces weight, hypertension and ameliorates glycemic control. Its action on adipose tissue distribution and in particular on epicardial adipose tissue EAT remains unknown. Whether metabolic improvement is associated with EAT reduction is also unknown.
The researchers thus investigated the effect of bariatric surgery on EAT in severely obese patients. The primary endpoint of this study was the change in EAT amount 6 months after bariatric surgery.
The best of our knowledge, no study has really addressed whether this EAT was modulated by diet or therapeutics like bariatric surgery. The researchers were particularly interested in studying the impact of bariatric surgery and of weight loss on the amount of EAT and whether reduction in EAT could have a positive impact on myocardial function.
Assistance Publique Hopitaux De Marseille is the lead sponsor of 686 studies on the registry; 148 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
35 patients addressed for severe obesity in the Endocrinology department of Marseille North Hospital before (V1) and 6 months (V2) after bariatric surgery
Procedure: bariatric surgery
The bariatric surgery is a relevant treatment for severely obese patients those with metabolic complications, as it significantly reduces weight, hypertension and ameliorates glycemic control.
The change in EAT amount 6 months after bariatric surgery.
We thus investigated the effect of bariatric surgery on EAT in severely obese patients.
Time frame: 36 months
Evaluation of 3 parameters
1. to evaluate the variation in myocardial, hepatic , pancreatic and triglyceride content 2. to evaluate the variation in left ventricular function or myocardial function 3. and to describe the relationships between changes in visceral abdominal fat, subcutaneous fat and epicardial fat
Time frame: 36 months
This study is completed, as verified in Jul 2015. You cannot join it, but the record below documents what was studied.
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Assistance Publique Hopitaux De Marseille