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CompletedNCT01282840Updated Jan 15, 2019

Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.

An interventional study of Tolterodine SR in Lower Urinary Tract Symptoms, sponsored by Far Eastern Memorial Hospital. Completed at 1 site in Taiwan. Open to female participants aged 20 Years to 99 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-15.

Sponsored by Far Eastern Memorial Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 6 months after the study started (first participant enrolled Jul 2010, registered Jan 2011).
Phase
Not applicable
Study type
Interventional
Enrollment
676
Allocation
Not applicable
Ages
20 Years to 99 Years
Sex
Female
01

Study summary

Overactive bladder syndrome (OAB) affects around 17 % of female population. However, the etiology of OAB is complicated and unclear in many aspects. Bladder wall thickness had been reported to be strongly associated with OAB, but its use as a screening tool remains controversial. Besides, few studies reported patterns of sexual dysfunction in female patients with lower urinary tract symptoms (LUTS). Therefore the aims of our study were to analyze the bladder wall blood perfusion pattern in female LUTS patients, the association of between the bladder wall blood perfusion pattern and the efficacy of anti-muscarinic treatment for female OAB, and the patterns of sexual dysfunction in the female LUTS patients.

02

Conditions studied

  • Lower Urinary Tract Symptoms

Keywords

  • LUTS
03

In context

Lower Urinary Tract Symptoms

406 studies on the registry are indexed under Lower Urinary Tract Symptoms; 110 are open to participants now.

This study's enrollment of 676 is above the median of 93 across 260 interventional studies indexed under Lower Urinary Tract Symptoms.

Browse Lower Urinary Tract Symptoms studies →

Lead sponsor

Far Eastern Memorial Hospital is the lead sponsor of 253 studies on the registry; 38 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 99 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • all cases are female patients with lower urinary tract symptoms

Exclusion criteria

Exclusion Criteria:

  • nil
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
676 participants (actual)

Study arms

  • Other
    Bladder wall blood perfusion pattern

    Drug: Tolterodine SR

Interventions

  • DrugTolterodine SR

    Tolterodine SR 4 mg qd

06

What researchers measure

Primary outcomes

  1. Blood flow pattern after antimuscarinics

    Time frame: 12 weeks

Secondary outcomes

  1. Blood flow patterns between different LUTS subgroups

    Time frame: 1 day

07

Study locations

1 site
  • Far Eastern Memorial Hospital
    New Taipei, Banqiao 22060, Taiwan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 15, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01282840
Lead sponsor
Far Eastern Memorial Hospital
Collaborators
National Science Council, Taiwan
Responsible party
Sheng-Mou Hsiao (Chief, Department of Obstetrics & Gynecology, Far Eastern Memorial Hospital) — Principal investigator
First posted
Jan 25, 2011
Start date
Jul 20, 2010
Primary completion
Nov 5, 2018
Completion
Dec 26, 2018
Last update
Jan 15, 2019
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2018. You cannot join it, but the record below documents what was studied.

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