An observational study in Hypoxia, sponsored by AGIR à Dom. Status unknown at 1 site in France. Open to female participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-02-28.
Sponsored by AGIR à Dom · Observational
Altitude tolerance correlates with the level of oxygenation achieved. The aim of the present study is to investigate whether increased expiratory pressure within the thorax is able to improve oxygenation during hypoxic hypoxia.
Two types of procedures will be tested in a random order, interspaced by resting periods : threshold PEEP set at 5,10 and 15 cm of water and pursed leap breathing.
Subjects will be tested at rest, and during light exercise (30% of sea level predicted VO2max).
FiO2 will be set at 12.5% (4000 m). fc, VE, PETCO2, TA, ECG, cardiac output, and tissular oxygenation will be monitored.
1,246 studies on the registry are indexed under Hypoxia; 239 are open to participants now.
This study's planned enrollment of 20 is below the median of 68 across 338 observational studies indexed under Hypoxia.
Browse Hypoxia studies →AGIR à Dom is the lead sponsor of 17 studies on the registry; 2 are open to participants now.
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community sample with mounteneering experience
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Exclusion Criteria :
with and without high altitude intolerance
Device: threshold PEEP
Various set of pressures : 0, 5, 10 cm H20; pursed lips breathing
SpO2
after three minutes of PEEP vs spontaneous breathing
Time frame: mean over 1 minute
peripheral HbO2/DeoxyHb
after three minutes of PEEP / PLB vs. spontaneous breathing
Time frame: 1 min
cardiac output
after three min of PEEP vs. spontaneous breathing
Time frame: mean over 1 min
pattern of breathing (fR, VT, PETCO2)
after three min of PEEP vs. spontaneous breathing
Time frame: 1 min
This study is status unknown, as verified in Feb 2012. You cannot join it, but the record below documents what was studied.
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AGIR à Dom