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CompletedNCT01239433Updated Sep 27, 2016

Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions

An observational study in Respiratory Failure, sponsored by Oslo University Hospital. Completed at 1 site in Norway. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-09-27.

Sponsored by Oslo University Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
25
Ages
18 Years and older
Sex
All
01

Study summary

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation.

Read the detailed description

Airway pressures change during fiberoptic bronchoscopy and endotracheal suctioning. In this study such pressure changes are examined in a mechanical lung model and in a population of ICU patients on mechanical ventilation. A systematic recording of airway pressures, tidal volumes and blood gases are carried out during ordinary therapeutic procedures requested by the staff physician. No additional study interventions are carried out.

The aim of the project is to examine negative effects of pressure/volume changes.

02

Conditions studied

  • Respiratory Failure
03

In context

Respiratory Insufficiency

1,675 studies on the registry are indexed under Respiratory Insufficiency; 300 are open to participants now.

This study's enrollment of 25 is below the median of 100 across 556 observational studies indexed under Respiratory Insufficiency.

Browse Respiratory Insufficiency studies →

Lead sponsor

Oslo University Hospital is the lead sponsor of 830 studies on the registry; 146 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients in the Intensive Care Unit (ICU) on mechanical ventilation where daily endotracheal suctioning is performed to remove secretions.

Most of the patients have ARDS/ ALI.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • > 18 years of age
  • on mechanical ventilation
  • daily endotracheal suctioning performed

Exclusion criteria

Exclusion Criteria:

  • \< 18 years of age
  • non-invasive ventilation
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
25 participants (actual)

Groups and cohorts

  • mechanically ventilated patients

    ICU patients on mechanical ventilation. Daily endotracheal suctioning performed to reduce secretions. Data recorded during these therapeutic interventions.

06

What researchers measure

Primary outcomes

  1. Intrabronchial airway pressure

    Time frame: 2013

07

Study locations

1 site
  • Oslo University Hospital - Ulleval
    Oslo, Oslo 0407, Norway
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 27, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01239433
Responsible party
Espen Rostrup Nakstad (MD, Oslo University Hospital) — Principal investigator
First posted
Nov 11, 2010
Start date
May 2011
Primary completion
May 2016
Completion
May 2016
Last update
Sep 27, 2016

Study contacts

Espen R Nakstad, MD
principal investigator · Oslo University Hospital - Ulleval, Norway
Helge Opdahl, MD, PhD
study director · Ullevaal University Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

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