An interventional study of probiotic and probiotic in Allergic Rhinitis, sponsored by Société des Produits Nestlé (SPN). Completed at 1 site in Switzerland. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-03-05.
Sponsored by Société des Produits Nestlé (SPN) (part of Nestlé S.A.) · Not applicable, Interventional, and Treatment
Various studies in animal and humans have shown a potential beneficial effect of probiotics consumption on allergy. However few studies exist that document their efficacy for upper airways allergies such as allergic rhinitis. The objective of this study is to investigate the effect of short-term oral administration of a L. paracasei or of a blend of 2 probiotics (L. acidophilus + B. lactis) on a nasal provocation test (NPT) with grass pollen, performed out of the pollen season. Adult volunteers with allergic rhinitis are enrolled in a randomized, double-blind study, based on two 4-weeks cross-over periods of product consumption separated by a washout period of 6-8 weeks. Objective and subjective clinical parameters of NPT as well as systemic and nasal immunological markers are compared before and after each treatment.
1,042 studies on the registry are indexed under Rhinitis, Allergic; 91 are open to participants now.
This study's enrollment of 30 is below the median of 90 across 858 interventional studies indexed under Rhinitis, Allergic.
Browse Rhinitis, Allergic studies →Société des Produits Nestlé (SPN) is the lead sponsor of 324 studies on the registry; 16 are open to participants now.
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Exclusion Criteria:
L. paracasei
Dietary Supplement: probiotic
L. acidophilus + B. lactis
Dietary Supplement: probiotic
Nasal reaction threshold when provocation test with allergens
Time frame: 4 weeks
This study is completed, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Probiotic
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