An observational study in Congenital Heart Defects, sponsored by Air Force Military Medical University, China. Status unknown at 1 site in China. Open to participants aged 2 Years to 12 Years. Per ClinicalTrials.gov, last updated 2011-06-23.
Sponsored by Air Force Military Medical University, China · Observational
The purpose of this study is to determine whether electroacupuncture preconditioning would provide protection against myocardial Ischemic-Reperfusion injury and systemic inflammation in children undergoing CPB for repair of congenital heart defects.
2-12 years old children undergoing repair of congenital heart defects were included, except for those with server pulmonary arterial hypertension, chromosomal defects, airway and parenchymal lung disease, immunodeficiency, or blood disorders were excluded. Children were equal randomized to EAPC(electroacupuncture preconditioning)or control group. Electroacupuncture was administered on the bilateral P6 acupoint after anesthesia induction, but prior to surgery in EAPC group. Control patients underwent sham placement of the electrode the arm without stimulation. The duration of cardiopulmonary bypass and aortic cross-clamp time was recorded. Myocardial injury was assessed by cardiac heart-type fatty acid-binding protein (HFAP) and cardiac troponin I (cTnI>0.40 ng/mL). 8-isoprostane , C-reactive protein, cytokines were measured pre- and postoperatively.
1,007 studies on the registry are indexed under Heart Defects, Congenital; 257 are open to participants now.
This study's planned enrollment of 60 is below the median of 121 across 442 observational studies indexed under Heart Defects, Congenital.
Browse Heart Defects, Congenital studies →Air Force Military Medical University, China is the lead sponsor of 172 studies on the registry; 36 are open to participants now.
Counted across the registry records on this site, refreshed daily.
2-12 years old children undergoing all types of open-heart surgery were included.
Exclusion Criteria:
Device: Electrical acupuncture stimulation
electroacupuncture would be administered on the bilateral P6 acupoint after anesthesia induction, but prior to surgery.
Also known as: Suzhou Hua Tuo Medical Instruments Co, Ltd, Suzhou, China
This study is status unknown, as verified in Oct 2010. You cannot join it, but the record below documents what was studied.
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Air Force Military Medical University, China