An observational study in 1- Women, 2- HIV Infection and 3- Followed in West Indies and French Guiana for His Infection, sponsored by University Hospital Center of Martinique. Completed at 1 site in Martinique. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2014-10-30.
Sponsored by University Hospital Center of Martinique · Observational
Cervical cancer is a public health problem. In term of frequency and mortality, it represents in Martinique the third localization the most frequently diagnosed and the fifth cause of death by cancer. Cervical cancer is recognized as viro-inducted. Human papillomavirus (HPV) is the etiologic agent, as a necessary but not sufficient cause, in the cancer genesis. It is estimated than about 70 to 80% of women have been or will be infected with an HPV in their genital life, the risks factors being those of the others sexually transmitted diseases (STD). Most of HPV infection are transient, by spontaneous clearance in a few months of the virus under episomal form.
Carcinogen risk is related to viral persistency which inducts the condition of cellular transformation.
Infection persistency and subsequent carcinogen risk depend of the genotype concerned and of the host immunitary response.
HIV infection is known to be associated with an higher prevalency of one or several infection with HPV-HR.
However, no data about HIV/HPV coinfection prevalency are available nowadays in French overseas department of South America whereas they are the most affected by HIV.
6,687 studies on the registry are indexed under Infections; 807 are open to participants now.
This study's enrollment of 455 is above the median of 240 across 2,136 observational studies indexed under Infections.
Browse Infections studies →University Hospital Center of Martinique is the lead sponsor of 77 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult HIV-Infected women followed in one of the center participating in the study and who has accepted the use of Nadis® medical files.
Exclusion Criteria:
Cervix cells
Presence of human papillomavirus
Presence of human papillomavirus in women's cervical smear infected with HIV and followed in West Indies and French Guiana
Time frame: 1 day
Characterization of Human papillomavirus genotypes
Characterization of Human papillomavirus genotype found in women's cervical smear infected with HIV and followed in West Indies and French Guiana
Time frame: 1 day
Presence and the severity of cervical injuries.
Time frame: 1 day
This study is completed, as verified in Oct 2014. You cannot join it, but the record below documents what was studied.
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University Hospital Center of Martinique