An interventional study of Perceptual learning and Video Game in Amblyopia, sponsored by University of California, Berkeley. Completed at 1 site in United States. Open to participants aged 5 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-17.
Sponsored by University of California, Berkeley · Not applicable, Interventional, and Basic science
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This study uses psychophysical measures to study neural plasticity in adults with amblyopia.
Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. Our previous findings (see CITATIONS) show that the adult amblyopic brain is still plastic and malleable, suggesting that active approach is potential useful in treating amblyopia. The goal of this project is to assess the limits and mechanisms of neural plasticity in amblyopic spatial vision. This study uses psychophysical measures to study neural plasticity in adults with amblyopia. Research participants will be asked to play video games with the amblyopic eye for a period of time. A range of visual functions will be monitored during the course of treatment.
183 studies on the registry are indexed under Amblyopia; 43 are open to participants now.
This study's enrollment of 20 is below the median of 60 across 133 interventional studies indexed under Amblyopia.
Browse Amblyopia studies →University of California, Berkeley is the lead sponsor of 106 studies on the registry; 18 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Behavioral: Perceptual learning
Behavioral: Video Game
Behavioral: Crossover (Occlusion therapy + Video Game)
Research participants will be asked to practice a visual discrimination task (e.g. position acuity, contrast sensitivity, stereoacuity etc) in our laboratory for a period of time (2 hrs/day, 5 days/week).
Also known as: vision therapy, vision training
Research participants will be asked to play "off-the-shelf" video games in our laboratory for a period of time (2 hrs/day, 5 days/week).
Also known as: vision therapy, vision training
Phase 1. Research participants will be required to cover the good eye during the day in order to push the brain to use the amblyopic eye (2 hrs/day, 5 days/week for 2-4 weeks). Phase 2. Research participants will be required to cover the good eye during the day in order to push the brain to use the amblyopic eye (2 hrs/day, 5 days/week for 2-4 weeks).
Also known as: vision therapy, vision training
Amblyopic vision
Improvement in amblyopic vision : visual acuity and stereoacuity
Time frame: 9 months
Spatial vision
Improvement in spatial vision (positional acuity and spatial attention)
Time frame: 9 months
Temporal vision
Improvement in temporal processing and temporal vision (attentional blink)
Time frame: 9 months
Plan to share: Undecided
This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.
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University of California, Berkeley