Status unknownNCT01215994Updated Apr 21, 2015

Estimation of Glomerular Filtration Rate (GFR) in Patients With Type 2 Diabetes Mellitus.

An observational study in Diabetes Mellitus and Diabetic Nephropathy, sponsored by AHEPA University Hospital. Status unknown at 1 site in Greece. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2015-04-21.

Sponsored by AHEPA University Hospital · Observational

The sponsor has not verified this record recently (last verified Apr 2015), so the status shown — last known as Recruiting — may be out of date.

Study type: Observational
Time perspective: Cross-sectional
Enrollment: 600
Ages: 18 Years to 85 Years
Sex: All

Study summary

The purpose of the present study is to evaluate bias, precision and accuracy of new cystatin C and creatinine based equations for GFR estimation compared with 51Cr-EDTA (chromium-51 labeled ethylenediamine tetraacetic acid) measured GFR in patients with diabetes.

Read the detailed description

The purpose of the present study is to evaluate bias, precision and accuracy of new cystatin C and creatinine based equations for GFR estimation compared with 51Cr-EDTA measured GFR in patients with diabetes.

Additional, we will check which equation detects better the reduction of renal function over the time, in patients with diabetes.

Finally, we will investigate if cystatin C levels can be influenced by factors other than GFR

Conditions studied

Diabetes Mellitus
Diabetic Nephropathy

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In context

Diabetic Nephropathies

534 studies on the registry are indexed under Diabetic Nephropathies; 107 are open to participants now.

This study's planned enrollment of 600 is above the median of 154 across 142 observational studies indexed under Diabetic Nephropathies.

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Lead sponsor

AHEPA University Hospital is the lead sponsor of 34 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years to 85 Years
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

diabetic patients treated in the primary care clinic

Inclusion criteria

Type 2 and type 1 diabetes mellitus

Exclusion criteria

Exclusion Criteria:

Patients with other type diabetes: gestational, exocrine pancreatic defects, endocrinopathies, drugs
Patients with end-stage renal disease, cardiac failure, hepatic failure, malignancies, immunosuppression, pregnant, diabetic ketoacidosis

Study design

Time perspective: Cross-sectional
Enrollment: 600 participants (estimated)
Patient registry: No
Biospecimen retention: Samples without dna

Study locations

1 of 1 sites recruiting

AHEPA University Hospital of Thessaloniki
Thessaloniki, 54636, Greece
- Alexandra Ntemka, MD · Sub investigator
- Fotios Iliadis, PhD, MD · Principal investigator
Recruiting

References and documents

Publications

Iliadis F, Didangelos T, Ntemka A, Makedou A, Moralidis E, Gotzamani-Psarakou A, Kouloukourgiotou T, Grekas D. Glomerular filtration rate estimation in patients with type 2 diabetes: creatinine- or cystatin C-based equations? Diabetologia. 2011 Dec;54(12):2987-94. doi: 10.1007/s00125-011-2307-1. Epub 2011 Sep 23. PubMed 21947381 ↗

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Apr 21, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT01215994
Lead sponsor: AHEPA University Hospital
Responsible party: Fotios Iliadis (MD, ASSISTANT PROFESSOR, AHEPA University Hospital) — Principal investigator
First posted: Oct 7, 2010
Start date: Mar 2009
Primary completion: Mar 2016 (estimated)
Completion: Mar 2016 (estimated)
Last update: Apr 21, 2015

Study contacts

Fotios Iliadis, MD, PhD

Contact

iliadis@med.auth.gr

2310993472 ext. 0030

Dimitrios Grekas, PhD, MD

study chair · Aristotle University of Thessaloniki, Greece

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2015. You cannot join it, but the record below documents what was studied.

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