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CompletedNCT01207635Updated Jul 30, 2012

Evaluation of Antiproliferative Effects of Arimidex in Ductal Lavage Fluid in Patients With Breast Cancer

An observational study in Breast Cancer, sponsored by M.D. Anderson Cancer Center. Completed at 1 site in United States. Open to female participants. Per ClinicalTrials.gov, last updated 2012-07-30.

Sponsored by M.D. Anderson Cancer Center · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
42
Sex
Female
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Study summary

The goal of this study is to evaluate antiproliferative effects of Arimidex in ductal lavage fluids of Breast Cancer patients.

Breast cancer is the leading cause of cancer incidence and the second leading cause of cancer mortality in women. Breast duct fluid provide biomarkers to aid in risk assessment of developing breast cancer.

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Conditions studied

  • Breast Cancer

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Keywords

  • Cancer
  • Arimidex
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In context

Breast Neoplasms

12,543 studies on the registry are indexed under Breast Neoplasms; 2,892 are open to participants now.

This study's enrollment of 42 is below the median of 184 across 2,642 observational studies indexed under Breast Neoplasms.

Browse Breast Neoplasms studies →

Lead sponsor

M.D. Anderson Cancer Center is the lead sponsor of 2,999 studies on the registry; 581 are open to participants now.

Of its 599 completed or terminated interventional studies of FDA-regulated products, 402 (67%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Breast cancer patients receiving standard Arimidex treatment.

Inclusion criteria

  • Patient must have a history of breast cancer.
  • Patient must be scheduled to receive standard treatment with Arimidex for adjuvant hormonal management.
  • Patient must be willing to undergo a duct lavage.
  • Patient must sign an Informed Consent.

Exclusion criteria

Exclusion Criteria:

  • None.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
42 participants (actual)
Biospecimen retention
None retained

Groups and cohorts

  • Breast Cancer Patients

    Procedure: Ductal Lavage Fluid Collection

Interventions

  • ProcedureDuctal Lavage Fluid Collection

    Procedure of inserting a small catheter into the ductal openings in the nipple and washing out cells from inside the duct.

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What researchers measure

Primary outcomes

  1. Number of Patients with Antiproliferative Effects of Arimidex

    Biomarker modulation study on effects of Armimidex in ductal lavage fluid from evaluable epithelial cells specimen.

    Time frame: Study duration 4 years

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Study locations

1 site
  • UT MD Anderson Cancer Center
    Houston, Texas 77030, United States
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References and documents

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 30, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01207635
Lead sponsor
M.D. Anderson Cancer Center
Responsible party
Sponsor
First posted
Sep 23, 2010
Start date
Nov 2002
Primary completion
Jan 2006
Completion
Jan 2006
Last update
Jul 30, 2012

Study contacts

Banu Arun, MD
study chair · UT MD Anderson Cancer Center

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2012. You cannot join it, but the record below documents what was studied.

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