An interventional study of Sev-I group and Sevo continuous inhalation in Brain Ischemia, sponsored by Xijing Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2010-09-20.
Sponsored by Xijing Hospital · Not applicable, Interventional, and Prevention
The current study is designed to clarify the neuroprotective effect of sevoflurane preconditioning on the patients underwent intracranial aneurysm surgery.
The current study is designed to clarify the neuroprotective effect of sevoflurane preconditioning on the patients underwent intracranial aneurysm surgery. The patients with cerebral aneurysm will be recruited in current study. The sevoflurane preconditioning will be performed before the surgical procedure. The neurological injury biomarkers, such as S-100b and NSE will be detected. The neurological function and recovery will be assessed after the surgery.
427 studies on the registry are indexed under Intracranial Aneurysm; 115 are open to participants now.
This study's planned enrollment of 80 is below the median of 110 across 207 interventional studies indexed under Intracranial Aneurysm.
Browse Intracranial Aneurysm studies →Xijing Hospital is the lead sponsor of 465 studies on the registry; 157 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients will receive the total intravenous anesthesia with propofol infusion during the surgery.
Patients will receive the anesthesia with continuous inhalation of sevoflurane.
Procedure: Sevo continuous inhalation
Sevoflurane will be given before the cerebral artery clip as a preconditioning procedure for the coming ischemia-reperfusion injury.
Procedure: Sev-I group
Sevoflurane will be given before the cerebral artery clip as a preconditioning procedure for the coming ischemia-reperfusion injury.
Also known as: Sevoflurane preconditioning
Patients will receive the anesthesia with continuous inhalation of sevoflurane.
S-100B,NSE
Time frame: 7 days
Karnofsky Performance Scale,NIH stroke index, MMSE
Time frame: 6 months
This study is status unknown, as verified in Aug 2009. You cannot join it, but the record below documents what was studied.
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Xijing Hospital