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CompletedNCT01179412Updated Aug 11, 2010

Treatment of Epidemic Keratoconjunctivitis With 2% Povidone-iodine

A Phase 4 interventional study of 2% povidone-iodine and 2% povidone-iodine in Viral Conjunctivitis, sponsored by Mahidol University. Completed at 1 site in Thailand. Open to participants aged 7 Years and older. Per ClinicalTrials.gov, last updated 2010-08-11.

Sponsored by Mahidol University · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
172
Allocation
Non-randomized
Ages
7 Years and older
Sex
All
01

Study summary

The purpose of this study is to determine the outcomes of treating epidemic keratoconjunctivitis with 2% povidone-iodine.

Read the detailed description

The study design was a prospective interventional case series. Our institutional ethical committee approved the study protocol in April 2004. We performed this study between July 2004 and December 2009. During this period, there were 2 episodes of EKC epidemic. The first episode was in 2006 and the second in 2009.

02

Conditions studied

  • Viral Conjunctivitis
03

In context

Conjunctivitis

361 studies on the registry are indexed under Conjunctivitis; 17 are open to participants now.

This study's enrollment of 172 is above the median of 100 across 299 interventional studies indexed under Conjunctivitis.

Browse Conjunctivitis studies →

Lead sponsor

Mahidol University is the lead sponsor of 731 studies on the registry; 116 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
7 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • patients who were diagnosed with EKC at the outpatient ophthalmic unit

Exclusion criteria

Exclusion Criteria:

  • children younger than six years
  • women being pregnant or during lactation
  • history of allergy to povidone-iodine
  • prior ocular surgery
  • contact lens usage and chronic eye diseases with current eye medications.
05

Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
172 participants (actual)

Study arms

  • Experimental
    2% povidone-iodine

    Drug: 2% povidone-iodine

Interventions

  • Drug2% povidone-iodine

    apply 4 times a day for one week

    Also known as: PVP-I

  • Drug2% povidone-iodine

    apply 2% povidone-iodine 4 times per day for one week

    Also known as: PVP-I

06

What researchers measure

Primary outcomes

  1. the recovery rate within one week of treatment

    Time frame: 1 week

Secondary outcomes

  1. drug tolerability

    proportion of patient who can continue topical application of povidone-iodine for a week or until EKC subsides

    Time frame: 1 week

07

Study locations

1 site
  • Department of Ophthalmology, Siriraj Hospital Mahidol University
    Bangkoknoi, Bangkok 10700, Thailand
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 11, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01179412
Lead sponsor
Mahidol University
First posted
Aug 11, 2010
Start date
Jul 2004
Primary completion
Dec 2009
Completion
Dec 2009
Last update
Aug 11, 2010

Study contacts

Adisak Trinavarat, MD
principal investigator · Siriraj Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2010. You cannot join it, but the record below documents what was studied.

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