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CompletedNCT01178957Updated Aug 7, 2013

Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

An observational study in Type 1 Diabetes, sponsored by University of Aarhus. Completed at 1 site in Denmark. Open to male participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2013-08-07.

Sponsored by University of Aarhus · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
8
Ages
18 Years to 50 Years
Sex
Male
01

Study summary

The purpose of this study is to estimate the acute effect of hyperglycemia on Very-Low-Density-Lipoprotein-triglyceride(VLDL-TG) secretion.

02

Conditions studied

  • Type 1 Diabetes

Keywords

  • Type 1 diabetes
  • Very-Low-Density-Lipoprotein(VLDL)
  • Hyperglycemia
03

In context

Diabetes Mellitus, Type 1

3,523 studies on the registry are indexed under Diabetes Mellitus, Type 1; 577 are open to participants now.

This study's enrollment of 8 is below the median of 120 across 748 observational studies indexed under Diabetes Mellitus, Type 1.

Browse Diabetes Mellitus, Type 1 studies →

Lead sponsor

University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Male
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Type 1 diabetics

Inclusion criteria

  1. Type 1 diabetes
  2. Age 18-50 years

Exclusion criteria

Exclusion Criteria:

  1. Smoking
  2. Alcohol abuse
  3. Use of medications (except insulin in diabetics)
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
8 participants (actual)
Biospecimen retention
Samples with dna

Groups and cohorts

  • Type 1 diabetes

    Other: Hyperglycemia

Interventions

  • OtherHyperglycemia

    Hyperglycemia with a blood glucose of 15 mmol/L

06

What researchers measure

Primary outcomes

  1. Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) secretion

    Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) kinetics over a single study day

    Time frame: 8 hours

07

Study locations

1 site
  • Department of Endocrinology MEA, Aarhus Hospital
    Aarhus C, 8000, Denmark
08

References and documents

Publications

  • Johansen RF, Sondergaard E, Sorensen LP, Nellemann B, Christiansen JS, Nielsen S. Isolated hyperglycaemia does not increase VLDL-triacylglycerol secretion in type 1 diabetic men. Diabetologia. 2015 Feb;58(2):355-62. doi: 10.1007/s00125-014-3422-6. Epub 2014 Nov 11. PubMed 25385409 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 7, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01178957
Lead sponsor
University of Aarhus
Responsible party
Sponsor
First posted
Aug 10, 2010
Start date
Apr 2012
Primary completion
Apr 2013
Completion
Apr 2013
Last update
Aug 7, 2013

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2013. You cannot join it, but the record below documents what was studied.

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