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CompletedNCT01178190NBIUpdated Aug 10, 2010

The Role of Narrow Band Imaging Videobronchoscopy in Lung Cancer

An observational study in Lung Cancer, sponsored by Asan Medical Center. Completed at 1 site in Korea, Republic of. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2010-08-10.

Sponsored by Asan Medical Center · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
101
Ages
19 Years and older
Sex
All
01

Study summary

Narrow band imaging (NBI) videobronchoscopy is an optical technique in which filtered light enhances superficial neoplasm based on their neoangiogenic pattern. The objectives of this study investigate its better diagnostic yield in the assessment of lung cancer than conventional flexible bronchoscopy.

Read the detailed description

Inspection with high resolution endoscopy was followed by NBI. Detected lesions were biopsied. applied the system of shibuya et al. to analyze and classify vascular patterns by NBI into four categories (spiral and screw pattern, dotted pattern, tortuous pattern, avascular pattern) compared with the known diagnostic yield of conventional white light bronchoscopy, An equivalent or superior result will also significantly impact on patient care This technology could aid not only early-stage lung cancer diagnosis but also more accurate local staging of lung cancer.

02

Conditions studied

  • Lung Cancer

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Keywords

  • narrow band imaging
  • malignant lesion
  • lung cancer
  • NBI
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In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's enrollment of 101 is below the median of 189 across 1,514 observational studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Asan Medical Center is the lead sponsor of 562 studies on the registry; 71 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

suspected endobroncheal lesion on chest CT

Inclusion criteria

  • endobronchial lesion on chest CT

Exclusion criteria

Exclusion Criteria:

  • Age \< 18 years old
  • Inability to consent for the study
  • Inability to tolerate bronchoscopy
  • Active pulmonary infection (bronchitis, pneumonia)
  • ST elevation or depression on ECG
  • Prothrombin time prolongation(\<70%)
  • platelet \<10,000
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
101 participants (actual)

Groups and cohorts

  • lung cancer
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What researchers measure

Primary outcomes

  1. accuracy of NBI videobronchoscopic biopsy

    Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for lung cancer.

    Time frame: 10-11 months

Secondary outcomes

  1. early cancer lesion detection rate using Shibuya descriptors

    Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for early lung cancer.

    Time frame: 10-11 months

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Study locations

1 site
  • ChangMin, Choi
    Seoul, Korea, Republic of
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 10, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01178190
Lead sponsor
Asan Medical Center
First posted
Aug 10, 2010
Start date
Jul 2009
Primary completion
Jun 2010
Completion
Jun 2010
Last update
Aug 10, 2010

Study contacts

ChangMin Choi, M.D.
principal investigator · Asan Medical Center

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2010. You cannot join it, but the record below documents what was studied.

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