CClinicalTrials.gg
CompletedNCT01126723Updated Dec 19, 2023Results posted

Effects of Tai Chi on Frailty in Elderly Adults

An interventional study of Tai Chi and Education-Control in Frailty, sponsored by Hebrew SeniorLife. Completed at 1 site in United States. Open to participants aged 70 Years and older. Per ClinicalTrials.gov, last updated 2023-12-19.

Sponsored by Hebrew SeniorLife · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
66
Allocation
Randomized
Ages
70 Years and older
Sex
All
01

Study summary

The aim of this study is determine the effects of Tai Chi exercise, as compared to an education-based control intervention, on cardiovascular and balance system function in older people at risk of developing frailty. We hypothesize that long-term Tai Chi training will improve specific nonlinear properties associated of cardiovascular and balance dynamics in this population.

02

Conditions studied

  • Frailty

Browse trials for

03

In context

Frailty

1,199 studies on the registry are indexed under Frailty; 430 are open to participants now.

This study's enrollment of 66 is below the median of 80 across 681 interventional studies indexed under Frailty.

Browse Frailty studies →

Lead sponsor

Hebrew SeniorLife is the lead sponsor of 36 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
70 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Men and women over age 70 will be included if they are able to stand and walk unassisted, are free of any acute or unstable medical conditions, and are able to understand directions and participate in the protocol.

Exclusion criteria

Exclusion Criteria:

  • Potential subjects will be excluded 1) if they cannot stand and ambulate unassisted, 2) are experiencing any symptomatic cardiovascular or respiratory disease, or have 3) a myocardial infarction or stroke within 6 months, 4) painful arthritis, spinal stenosis, amputation, painful foot lesions, or neuropathy that limits balance and mobility, 5) systolic BP above 160 or diastolic BP above 100 mm Hg, 6) a cardiac pacemaker, 7) Parkinson's Disease or other neuromuscular disorder, 8) metastatic cancer or immunosuppressive therapy, or 9) have significant visual impairment.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
66 participants (actual)

Study arms

  • Experimental
    Tai Chi group

    Other: Tai Chi

  • Active comparator
    Educational Control group

    Other: Education-Control

Interventions

  • OtherTai Chi

    The Tai Chi intervention will consist of a 12 week, instructor-led, group-based Tai Chi training program (two, one-hour sessions per week).

  • OtherEducation-Control

    The Education-Control intervention consists of a 12 week, instructor-led attention control program consisting of health education and mind-body breathing exercises (two, one-hour sessions per week)

06

What researchers measure

Primary outcomes

  1. Frailty Index

    Frailty is defined as the combination of unintentional weight loss, exhaustion, low physical activity, slow walking speed, and muscular weakness.

    Time frame: post-intervention

07

Results

Posted Jan 30, 2015

Participant flow

Participant flow — Overall Study
MilestoneTai Chi GroupEducational Control Group
Started3531
Completed2928
Not completed63

Outcome measures

PrimaryFrailty Index

Frailty is defined as the combination of unintentional weight loss, exhaustion, low physical activity, slow walking speed, and muscular weakness.

Time frame:
post-intervention
Reported as:
Number · participants
Frailty Index
participantsTai Chi GroupEducational Control Group
Frail75
Prefrail1621
Nonfrail62
Statistical analysis
  • Tai Chi Group vs Educational Control Group · Fisher Exact · p = 0.15 (The a priori threshold for statistical significance was set to 0.05.)

Adverse events

Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Tai Chi Group—0/35 (0%)0/35 (0%)
Educational Control Group—0/31 (0%)0/31 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)Tai Chi GroupEducational Control GroupTotal
Mean87 ± 586 ± 687 ± 6
Sex: Female, Male
Sex: Female, Male(Participants)Tai Chi GroupEducational Control GroupTotal
Female7714
Male282452
Frailty Index
Frailty Index(participants)Tai Chi GroupEducational Control GroupTotal
Frail10616
Prefrail202343
Nonfrail527
08

Study locations

1 site
  • Hebrew Rehabilitation Center
    Roslindale, Massachusetts 02131, United States
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 19, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01126723
Lead sponsor
Hebrew SeniorLife
Collaborators
National Institutes of Health (NIH), National Institute on Aging (NIA)
Responsible party
Sponsor
First posted
May 20, 2010
Start date
Sep 2010
Primary completion
Sep 2013
Completion
Sep 2013
Results posted
Jan 30, 2015
Last update
Dec 19, 2023

Study contacts

Lewis Lipsitz, MD
principal investigator · Hebrew Rehabilitation Center

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion