An observational study in Uterine Inertia and Dystocia, sponsored by Centre Hospitalier Universitaire de Nīmes. Terminated at 1 site in France. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-11-19.
Sponsored by Centre Hospitalier Universitaire de Nīmes · Observational
Despite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists. This study is a pilot study whose aim is to test the hypothesis that an association between uterine dystocia and single-nucleotide polymorphisms (SNPs) in the genes coding for the LXRs.
39 studies on the registry are indexed under Uterine Inertia; 7 are open to participants now.
Browse Uterine Inertia studies →Centre Hospitalier Universitaire de Nīmes is the lead sponsor of 595 studies on the registry; 90 are open to participants now.
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The study population represents women undergoing a difficult, stagnating labor due to either physical or uterine dystocia.
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Exclusion Criteria:
Control group: these patients have mechanical dystocia; cholesterol metabolism factors are a priori not involved.
Biological: Whole blood sampling
These patients have uterine dystocia
Biological: Whole blood sampling
Whole blood sampling for SNP polymorphism analysis
The multi-loci genotype of the target DNA sequence.
The polymorphisms of interest are the following SNPs: rs3758673, rs3758674, rs12221497, rs11039155, rs2279238, rs7120118, rs35463555, rs1052533, rs2248949, rs41432149, rs1405655, rs4802703.
Time frame: Day 1
This study is terminated, as verified in Nov 2015. You cannot join it, but the record below documents what was studied.
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