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CompletedNCT01099241Updated Apr 6, 2010

Central Venous Pressure (CVP) Assessment by Ultrasound and Physical Examination

An observational study in Central Venous Pressure, sponsored by University of Iowa. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-04-06.

Sponsored by University of Iowa · Observational

Study type
Observational
Time perspective
Prospective
Enrollment
38
Ages
18 Years and older
Sex
All
01

Study summary

Ultrasound may be useful for noninvasively determining the central venous pressure. We intend to compare the clinical examination of the neck veins; ultrasound delineation of the internal jugular vein; and the central venous pressure measured with an intravascular catheter.

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Conditions studied

  • Central Venous Pressure

Keywords

  • CVP
  • US
  • Ultrasonography
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In context

Lead sponsor

University of Iowa is the lead sponsor of 276 studies on the registry; 35 are open to participants now.

Of its 44 completed or terminated interventional studies of FDA-regulated products, 39 (89%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients admitted to Intensive care unit.

Inclusion criteria

  • adult medical or surgical ICU patients who have preexisting central venous (jugular/subclavian only) catheters.

Exclusion criteria

Exclusion Criteria:

  • subjects with only a femoral venous catheter.
  • subjects whose CVP measurement by the indwelling catheter exceeds 20cm of water.
  • subjects younger than 18 years old.
  • inability to obtain informed consent from the subject or the subjects authorized representative.
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Study design

Time perspective
Prospective
Enrollment
38 participants (actual)
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What researchers measure

Primary outcomes

  1. Correlation of CVP measurement via ultrasound and central venous catheter

    CVP as determined non-invasively with the transcutaneous ultrasound probe will correlate with a high degree of accuracy to the measurement obtained invasively by the catheter and pressure transducer.

    Time frame: At data collection: this is a physiologic study

Secondary outcomes

  1. Correlation of CVP measurement via physical examination of IJV and EJV.

    Despite its more tortuous course and smaller caliber, the external jugular vein will be as reliable (compared to the catheter) as the internal jugular to estimate CVP

    Time frame: At data collection: physiologic study

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Study locations

1 site
  • University of Iowa
    Iowa City, Iowa 52246, United States
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References and documents

Publications

  • Baumann UA, Marquis C, Stoupis C, Willenberg TA, Takala J, Jakob SM. Estimation of central venous pressure by ultrasound. Resuscitation. 2005 Feb;64(2):193-9. doi: 10.1016/j.resuscitation.2004.08.015. PubMed 15680529 ↗
  • Bazaral M, Harlan S. Ultrasonographic anatomy of the internal jugular vein relevant to percutaneous cannulation. Crit Care Med. 1981 Apr;9(4):307-10. doi: 10.1097/00003246-198104000-00004. PubMed 7214938 ↗
  • Cook DJ. Clinical assessment of central venous pressure in the critically ill. Am J Med Sci. 1990 Mar;299(3):175-8. doi: 10.1097/00000441-199003000-00006. PubMed 2316561 ↗
  • Davison R, Cannon R. Estimation of central venous pressure by examination of jugular veins. Am Heart J. 1974 Mar;87(3):279-82. doi: 10.1016/0002-8703(74)90064-7. No abstract available. PubMed 4812363 ↗
  • Lipton B. Estimation of central venous pressure by ultrasound of the internal jugular vein. Am J Emerg Med. 2000 Jul;18(4):432-4. doi: 10.1053/ajem.2000.7335. PubMed 10919533 ↗
  • Lipton BM. Determination of elevated jugular venous pressure by real-time ultrasound. Ann Emerg Med. 1999 Jul;34(1):115. doi: 10.1016/s0196-0644(99)70287-8. No abstract available. PubMed 10409088 ↗
  • Rizvi K, Deboisblanc BP, Truwit JD, Dhillon G, Arroliga A, Fuchs BD, Guntupalli KK, Hite D, Hayden D; NIH/NHLBI ARDS Clinical Trials Network. Effect of airway pressure display on interobserver agreement in the assessment of vascular pressures in patients with acute lung injury and acute respiratory distress syndrome. Crit Care Med. 2005 Jan;33(1):98-103; discussion 243-4. doi: 10.1097/01.ccm.0000150650.70142.e9. PubMed 15644654 ↗
  • Vinayak AG, Levitt J, Gehlbach B, Pohlman AS, Hall JB, Kress JP. Usefulness of the external jugular vein examination in detecting abnormal central venous pressure in critically ill patients. Arch Intern Med. 2006 Oct 23;166(19):2132-7. doi: 10.1001/archinte.166.19.2132. PubMed 17060544 ↗
  • Deol GR, Collett N, Ashby A, Schmidt GA. Ultrasound accurately reflects the jugular venous examination but underestimates central venous pressure. Chest. 2011 Jan;139(1):95-100. doi: 10.1378/chest.10-1301. Epub 2010 Aug 26. PubMed 20798190 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 6, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01099241
Lead sponsor
University of Iowa
First posted
Apr 6, 2010
Start date
Aug 2007
Primary completion
Mar 2010
Completion
Mar 2010
Last update
Apr 6, 2010

Study contacts

Gregory A Schmidt
principal investigator · Roy J. & Lucille A. Carver College of Medicine, University of Iowa

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2010. You cannot join it, but the record below documents what was studied.

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