CClinicalTrials.gg
Status unknownNCT01081925Updated Mar 5, 2010

Congestive Heart Failure: Causes of Sudden Worsening

An observational study in Congestive Heart Failure, sponsored by University Hospital Hradec Kralove. Status unknown at 1 site in Czech Republic. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-03-05.

Sponsored by University Hospital Hradec Kralove · Observational

The sponsor has not verified this record recently (last verified Feb 2010), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of the study is to recognize main causes of acute decompensation of chronic congestive heart failure.

Read the detailed description

Congestive heart failure (CHF) presents a very significant cause of morbidity and mortality. The prevalence of CHF is between 2 and 4% and rises with age (in 70- to 80-year-old people is between 10 and 20%). CHF is the cause of 5% of all acute hospital admissions and accounts for 2% of expenses on health. The most common causes of worsening of the chronic CHF are ischemia, arrhythmias, valvular dysfunction, systemic or pulmonary hypertension, volume overload or fluid retention, high output conditions (infection, anemia, thyrotoxicosis), drugs (NSAIDs, cyclo-oxygenase (COX) inhibitors, thiazolidinediones) and medication nonadherence. The goal of this study is to determine the proportion of various reasons of acute worsening of CHF, using commonly available methods including assessment of serum drug levels.

02

Conditions studied

  • Congestive Heart Failure

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Keywords

  • Congestive Heart Failure
  • Cardiac Failure
03

In context

Heart Failure

5,697 studies on the registry are indexed under Heart Failure; 1,219 are open to participants now.

This study's planned enrollment of 100 is below the median of 200 across 1,678 observational studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

University Hospital Hradec Kralove is the lead sponsor of 46 studies on the registry; 13 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients suffering from sudden worsening of congestive heart failure, who are examined at the Emergency department or admitted to University Hospital

Inclusion criteria

  • able to provide informed consent
  • aged 19 years or more
  • history of heart failure of at least one month
  • examined or hospitalized for acute dyspnea at rest or with minimal exertion
  • clinical signs of fluid overload defined as at least one of following:
  • rales
  • jugular venous distension
  • peripheral edema
  • pulmonary congestion on X-ray
  • NT-proBNP above 210 pmo/l

Exclusion criteria

Exclusion Criteria:

  • none
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
100 participants (estimated)

Groups and cohorts

  • Congestive heart failure

    Patients suffering from sudden worsening of congestive heart failure

06

Study locations

1 of 1 sites recruiting
  • University Hospital Hradec Kralove
    Hradec Kralove, 50005, Czech Republic
    • Radek Pelouch · Principal investigator
    • Jiri Ceral, MD · Sub investigator
    • Miroslav Solar, MD · Sub investigator
    Recruiting
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 5, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT01081925
Lead sponsor
University Hospital Hradec Kralove
First posted
Mar 5, 2010
Start date
Feb 2010
Primary completion
Feb 2012 (estimated)
Completion
Feb 2012 (estimated)
Last update
Mar 5, 2010

Study contacts

Radek Pelouch, MD
Contact
pelouch@centrum.cz
00420495834740
Jiri Ceral, MD
Contact
ceral@seznam.cz
00420495832652
Radek Pelouch, MD
principal investigator · University Hospital Hradec Kralove

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2010. You cannot join it, but the record below documents what was studied.

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