An interventional study of Normal saline in Osteoarthritis, sponsored by The Catholic University of Korea. Completed at 1 site in South Korea. Open to female participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2010-02-02.
Sponsored by The Catholic University of Korea · Not applicable and Interventional
The purpose of this study is to assess the effects of joint effusion on proprioceptive status in patients with knee osteoarthritis (OA).
Proprioception is a sensory modality that provides feedback on the internal status of the body and enables us to perceive joint position and motion.
Osteoarthritis (OA), also called degenerative joint disease, is a major musculoskeletal condition characterized by loss of articular cartilage that leads to pain and loss of function. The most commonly affected joint is the knee, and OA may result in changes that affect not only intracapsular tissues, but also periarticular tissues, such as ligaments, capsules, tendons, and muscles. Many studies have examined the proprioceptive status of knee OA, and subjects with knee OA are known to have impaired proprioception compared with age-matched controls.
Joint effusion is a common symptom associated with chronic degenerative joint condition, but the effects of effusion on knee joint proprioception have not been investigated in detail.
A volume of 20 mL of normal saline was injected into the knee joint cavity of subjects in the experimental group under ultrasonographic guidance. Proprioceptive acuity was assessed by active repositioning of the lower limb using an electrogoniometer to measure knee joint position sense (JPS) under both non-weight-bearing and weight-bearing conditions twice, with a 20-min rest interval.
4,445 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 40 is below the median of 70 across 3,474 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →The Catholic University of Korea is the lead sponsor of 155 studies on the registry; 4 are open to participants now.
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Or at least two of criteria 2-6 established by the American College of Rheumatology (ACR):
Exclusion Criteria:
20cc saline infusion into the knee joint
Procedure: Normal saline
Procedure: Normal saline
20 cc normal saline injection into the knee joint
Proprioceptive acuity in Knee Joint. Proprioceptive acuity (difference between the knee angles at the target and reproduced positions) was assessed by active repositioning of the lower limb after injection or no injection.
Time frame: within one hour after intervention
This study is completed, as verified in Jan 2010. You cannot join it, but the record below documents what was studied.
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