An interventional study of Iron and Iron in Iron Overload, Oxidative Stress and Iron-deficiency Anemia, sponsored by University of California, Davis. Completed at 1 site in United States. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-05-30.
Sponsored by University of California, Davis · Not applicable, Interventional, and Basic science
Most breastfeeding women are told by their health care provider to continue taking prenatal vitamins after they give birth. A woman's requirement for iron while breastfeeding is low, yet prenatal vitamins contain a large amount of iron. The purpose of this study is to see if breastfeeding women are getting too much iron when taking prenatal vitamins.
Even though iron requirements are much lower for lactating women than for pregnant or non-pregnant, non-lactating women, and iron stores during lactation are often high due to release of iron from the additional maternal erythrocytes produced during pregnancy, iron supplements are often taken by lactating women in the U.S. Many studies have shown that higher iron status is associated with higher risk of certain chronic diseases (e.g. cancer and cardiovascular diseases). The overall goal of this proposed study is to understand the potential for oxidative stress due to iron supplementation, and possible mechanisms for these effects, and to identify safe and efficacious ways to ensure adequate iron status during lactation. The specific aims are:
644 studies on the registry are indexed under Anemia, Iron-Deficiency; 105 are open to participants now.
This study's enrollment of 114 is above the median of 100 across 503 interventional studies indexed under Anemia, Iron-Deficiency.
Browse Anemia, Iron-Deficiency studies →University of California, Davis is the lead sponsor of 798 studies on the registry; 146 are open to participants now.
Of its 65 completed or terminated interventional studies of FDA-regulated products, 43 (66%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Prenatal vitamin without iron plus capsule containing 27 mg of iron taken with meals
Dietary Supplement: Iron
Prenatal vitamin without iron plus capsule containing 27 mg of iron taken between meals
Dietary Supplement: Iron
Prenatal vitamin without iron plus capsule containing calcium carbonate (placebo) taken between meals
Dietary Supplement: Placebo
Iron as iron sulfate
Iron as iron sulfate
Placebo capsule
Oxidative stress
Isoprostane and 8-OHdG
Time frame: 3 month
Iron status
Ferritin, transferrin saturation, hepcidin
Time frame: 3 month
This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.
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University of California, Davis