An interventional study of Angiotensin II and Phenylephrine in Insulin Sensitivity and Microcirculation, sponsored by Maastricht University Medical Center. Completed at 1 site in Netherlands. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-12-02.
Sponsored by Maastricht University Medical Center · Not applicable, Interventional, and Basic science
In this study we hypothesize infusion of Angiotensin II improves the insulin-induced microvascular dilatation and therefore insulin-mediated glucose uptake. Objectives: Does infusion of Angiotensin II increase insulin-mediated glucose uptake via enhanced insulin-mediated microvascular function in healthy subjects?
1,960 studies on the registry are indexed under Insulin Resistance; 306 are open to participants now.
This study's enrollment of 18 is below the median of 40 across 1,536 interventional studies indexed under Insulin Resistance.
Browse Insulin Resistance studies →Maastricht University Medical Center is the lead sponsor of 835 studies on the registry; 122 are open to participants now.
Counted across the registry records on this site, refreshed daily.
1.18-60 years 2.Caucasian 3.Blood pressure \<140/90 mmHg.
Exclusion Criteria:
Placebo
Drug: Placebo
Angiotensin II
Drug: Angiotensin II
Phenylephrine
Drug: Phenylephrine
Angiotensin II
Phenylephrine
functional recruitment of capillaries in the skin
Time frame: January 2009
perfused capillary density in the nailfold
Time frame: January 2009
Endothelium- (in)dependent vasodilatation of finger skin microcirculation
Time frame: January 2006
Insulin sensitivity
Time frame: January 2009
This study is completed, as verified in Dec 2009. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Maastricht University Medical Center