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CompletedNCT01014819DermacorderUpdated Aug 3, 2011

A Clinical Trial of Dermacorder for Detecting Malignant Skin Lesions

An observational study in Basal Cell Carcinoma, sponsored by UCSF Benioff Children's Hospital Oakland. Completed at 1 site in United States. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2011-08-03.

Sponsored by UCSF Benioff Children's Hospital Oakland · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
30
Ages
18 Years to 75 Years
Sex
All
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Study summary

The Dermacorder measures the electric field in the skin. Malignant skin lesions disrupt the skin's normal electric field and this abnormal electric field can be detected by the Dermacorder. Therefore the investigators are testing the hypothesis that the Dermacorder can provide useful data to guide in the diagnosis of skin disease.

Read the detailed description

The Dermacorder is a non-invasive medical device that scans a probe over the skin about 200 microns away from it and detects the electric field in the skin using capacitative coupling. Measurements of hundreds of malignant melanomas in mice indicated that these lesions generate an electric field that is easily detected. One previous clinical trial at the VA Medical Center in Hampton VA indicated an 80% reliability in predicting malignant lesions by their electric field. We have improved the Dermacorder over the past two years by enhancing its sensitivity and stability and must now determine if these improvements have improved its ability to detect malignant lesions. If the Dermacorder provides a reliable diagnosis of malignant lesions, its use could dramatically reduce the number of biopsies performed and this would significantly improve the quality of life for hundreds of thousands of Americans seeking the advice of dermatologists regarding suspicious lesions each year

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Conditions studied

  • Basal Cell Carcinoma

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Keywords

  • Dermacorder
  • Electric field
  • basal cell carcinoma
  • Gorlin Syndrome
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In context

Carcinoma, Basal Cell

364 studies on the registry are indexed under Carcinoma, Basal Cell; 66 are open to participants now.

This study's planned enrollment of 30 is below the median of 138 across 92 observational studies indexed under Carcinoma, Basal Cell.

Browse Carcinoma, Basal Cell studies →

Lead sponsor

UCSF Benioff Children's Hospital Oakland is the lead sponsor of 53 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Males and females with multiple basal cell carcinomas

Inclusion criteria

  • Study subjects must have had diagnosed at least one benign or malignant skin lesion;
  • Subject is from 18-75 years of age, inclusive;
  • Subject must sign and date all informed consent statements.

Exclusion criteria

Exclusion Criteria:

  • Subject is exhibiting signs of a bacterial or viral infection, including fever;
  • Subject is unwilling to allow a biopsy of a malignant lesion for histological analysis.
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
30 participants (estimated)
06

Study locations

1 site
  • Childrens Hospital Oakland Research Institute
    Oakland, California 94609, United States
07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 3, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01014819
Lead sponsor
UCSF Benioff Children's Hospital Oakland
First posted
Nov 17, 2009
Start date
Oct 2009
Primary completion
Jul 2011
Completion
Jul 2011
Last update
Aug 3, 2011

Study contacts

Ervin Epstein, M.D.
principal investigator · UCSF Benioff Children's Hospital Oakland

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2011. You cannot join it, but the record below documents what was studied.

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