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Status unknownNCT00987883Updated Oct 1, 2009

The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

An observational study in Malnutrition, Gastroenterological Cancer and Surgical Procedures, Operative, sponsored by Peking Union Medical College Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2009-10-01.

Sponsored by Peking Union Medical College Hospital · Observational

The sponsor has not verified this record recently (last verified Sep 2009), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
18 Years to 80 Years
Sex
All
01

Study summary

Undernutrition is a state marked by energy and/or protein intake deficiency or mal-absorption, and is often described as protein energy malnutrition (PEM). Malnutrition is common in hospitalized patients worldwide. The prevalence of malnutrition in hospitalized patients range from 20% - 50%, depends on the varieties of diseases, health system, population and assessment tools. It is well documented in Western countries that malnutrition affects clinical outcomes negatively. Compared with well-nourished patients, patients with malnutrition stay longer in hospitals and related cost is significantly higher.

There is increasing evidence which indicates that appropriate nutrition support (e.g., standardized nutrition screening procedures, delivering nutrients with appropriate path, etc) may improve clinical outcome on malnutrition, along with cost saving.

To date, there is no study to document specifically the impact of malnutrition and related nutrition support on the health economics in China. Considering China now is on its way to establish public health security system and a diagnosis-related grouping system, the understanding of the cost effectiveness of nutrition support under the current clinical conditions is crucial.

This study aims to investigate the prevalence of perioperational malnutrition in gastroenterological cancer patient, the nutrition support status and related health economic effects.

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Conditions studied

  • Malnutrition
  • Gastroenterological Cancer
  • Surgical Procedures, Operative

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Keywords

  • Nutritional Support
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In context

Malnutrition

1,588 studies on the registry are indexed under Malnutrition; 237 are open to participants now.

This study's planned enrollment of 200 is close to the median of 203 across 388 observational studies indexed under Malnutrition.

Browse Malnutrition studies →

Lead sponsor

Peking Union Medical College Hospital is the lead sponsor of 1,115 studies on the registry; 463 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Hospitalization patient in a teaching hospital

Inclusion criteria

  • Age 18 or older
  • With gastroenterological cancer
  • Will receive resectional operation
  • Consent informed

Exclusion criteria

Exclusion Criteria:

  • With severly cardiac, pulmonary, liver or renal disease
  • With endocrine or metabolic disease
  • With dyslipidemia
  • Without consent
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)

Groups and cohorts

  • Malnutrition cohort

    The patients with undernutrition

  • Well nourished cohort

    Patient that well nourished and without undernutrition

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What researchers measure

Primary outcomes

  1. Cost

    Time frame: 30 days after operation

Secondary outcomes

  1. Mortality

    Time frame: 30 days after operation

  2. Infectious morbidity

    Time frame: 30 days after operation

  3. Length of hospitalization

    Time frame: 30 days after operation

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Study locations

1 of 1 sites recruiting
  • Peking Union Medical College Hospital
    Beijing, Beijing 100730, China
    Recruiting
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References and documents

Publications

  • Correia MI, Campos AC; ELAN Cooperative Study. Prevalence of hospital malnutrition in Latin America: the multicenter ELAN study. Nutrition. 2003 Oct;19(10):823-5. doi: 10.1016/s0899-9007(03)00168-0. PubMed 14559314 ↗
  • Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease-related malnutrition. Clin Nutr. 2008 Feb;27(1):5-15. doi: 10.1016/j.clnu.2007.10.007. Epub 2007 Dec 3. PubMed 18061312 ↗
  • Robinson G, Goldstein M, Levine GM. Impact of nutritional status on DRG length of stay. JPEN J Parenter Enteral Nutr. 1987 Jan-Feb;11(1):49-51. doi: 10.1177/014860718701100149. PubMed 3102782 ↗
  • Lochs H, Allison SP, Meier R, Pirlich M, Kondrup J, Schneider S, van den Berghe G, Pichard C. Introductory to the ESPEN Guidelines on Enteral Nutrition: Terminology, definitions and general topics. Clin Nutr. 2006 Apr;25(2):180-6. doi: 10.1016/j.clnu.2006.02.007. Epub 2006 May 11. PubMed 16697086 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 1, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00987883
Lead sponsor
Peking Union Medical College Hospital
First posted
Oct 1, 2009
Start date
Apr 2009
Primary completion
Dec 2009 (estimated)
Completion
Dec 2009 (estimated)
Last update
Oct 1, 2009

Study contacts

Wei Chen, M.D
Contact
txchenwei@gmail.com
86 10 65294095
Hua Jiang, M.D
Contact
cdjianghua@gmail.com
86 28 86741981
Wei Chen, M.D
study director · Peking Union Medical College Hospital
Chongmei Lu, M.D
study chair · Peking Union Medical College Hospital
Hua Jiang, M.D
principal investigator · Sichuan Academy of Medical Sciences

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2009. You cannot join it, but the record below documents what was studied.

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