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CompletedNCT00984529Updated Jan 7, 2011

Evaluation of Clinical Signs and Symptoms of Chronic Heart Failure in Patients Treated With Candesartan Cilexetil in Croatia

An observational study in Chronic Heart Failure, sponsored by AstraZeneca. Completed at 15 sites in Croatia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2011-01-07.

Sponsored by AstraZeneca · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
500
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to determine whether treatment with candesartan cilexetil for at least 6 months in patients with chronic heart failure improves clinical signs and symptoms of chronic heart failure.

02

Conditions studied

  • Chronic Heart Failure

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Keywords

  • Chronic heart failure
  • candesartan cilexetil
  • clinical signs
  • symptoms
03

In context

Heart Failure

5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.

This study's planned enrollment of 500 is above the median of 200 across 1,679 observational studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Primary Care

Inclusion criteria

  • Patients with diagnosed chronic heart failure
  • Patients treated for at least 6 months with candesartan cilexetil
  • Signed Informed consent

Exclusion criteria

Exclusion Criteria:

  • Hypersensitivity to candesartan cilexetil
  • Pregnancy / lactation
  • Severe hepatic impairment
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
500 participants (estimated)

Groups and cohorts

  • 1

    Cardiologist´s office patients

06

What researchers measure

Primary outcomes

  1. To evaluate clinical signs and symptoms of chronic heart failure (in terms of NYHA status, fluid retention and tiredness/fatigue) after at least 6 months of treatment with candesartan cilexetil

    Time frame: 1 visit (after at least 6 months of treatment)

Secondary outcomes

  1. To evaluate ventricular function after at least 6 months of treatment with candesartan cilexetil

    Time frame: 1 visit (after at least 6 months of treatment)

  2. To gain insight into usage of candesartan cilexetil in real life for chronic heart failure in Croatia

    Time frame: 1 visit (after at least 6 months of treatment)

  3. To evaluate patient's compliance with prescribed treatment

    Time frame: 1 visit (after at least 6 months of treatment)

07

Study locations

15 sites
  • Research Site
    Biograd, Croatia
  • Research Site
    Bjelovar, Croatia
  • Reserach Site
    Cakovec, Croatia
  • Research Site
    Karlovac, Croatia
  • Reserach Site
    Krapinske Toplice, Croatia
  • Research Site
    Novi Marof, Croatia
  • Research Site
    Opatija, Croatia
  • Research Site
    Osijek, Croatia
  • Research Site
    Pula, Croatia
  • Research Site
    Rijeka, Croatia
  • Reserach Site
    Sl. Brod, Croatia
  • Research Site
    Split, Croatia
  • Research Site
    Stubicke Toplice, Croatia
  • Reserach Site
    Zabok, Croatia
  • Research Site
    Zagreb, Croatia
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 7, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00984529
Lead sponsor
AstraZeneca
First posted
Sep 25, 2009
Start date
Sep 2009
Primary completion
Feb 2010
Completion
Feb 2010
Last update
Jan 7, 2011

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2011. You cannot join it, but the record below documents what was studied.

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