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CompletedNCT00968305Updated Aug 28, 2009

Interleukin (IL)-13 as a Marker in Pediatrics Asthma

An observational study in Asthma, sponsored by Rush University Medical Center. Completed at 1 site in United States. Open to participants aged 8 Years to 15 Years. Per ClinicalTrials.gov, last updated 2009-08-28.

Sponsored by Rush University Medical Center · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
19
Ages
8 Years to 15 Years
Sex
All
01

Study summary

Asthma is a very common childhood chronic illness and is generally more severe in African Americans. The investigators attempted to determine whether a specific immune marker is associated with lung function and asthma severity.

Read the detailed description

This study examined the relationship between Interleukin (IL)-13 from phytohemagglutinin-activated polymorphonuclear blood cells and asthma severity, lung function (measured as FEV1%), and total serum IgE levels in African American children with clinically diagnosed asthma

02

Conditions studied

  • Asthma

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Keywords

  • African American children with stable asthma
  • Asthma severity
  • Interleukin 13 from PHA stimulated PBMC
  • Lung function (FEV1%)
  • Total serum IgE
  • Pediatrics
03

In context

Asthma

3,921 studies on the registry are indexed under Asthma; 507 are open to participants now.

This study's enrollment of 19 is below the median of 150 across 970 observational studies indexed under Asthma.

Browse Asthma studies →

Lead sponsor

Rush University Medical Center is the lead sponsor of 394 studies on the registry; 61 are open to participants now.

Of its 30 completed or terminated interventional studies of FDA-regulated products, 25 (83%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
8 Years to 15 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

African-American children, ages 8 to 15 years, with clinically diagnosed asthma which had been stable for at least 4 weeks prior to enrollment in the study.

Inclusion criteria

  • African-American race, born in the U.S.
  • Age 8-15 years
  • Clinical diagnosis of asthma
  • Subject is able to understand and follow verbal instructions in English

Exclusion criteria

Exclusion Criteria:

  • Asthma exacerbation in the 4 weeks preceding the research visit
  • Oral/IV steroid use in the 4 weeks preceding the research visit
  • Upper or lower respiratory tract infection in the 4 weeks preceding the research visit
  • Antibiotic use in the 4 weeks preceding the research visit
  • Use of a short-acting bronchodilator during the 6 hours prior to spirometry (lung function testing)
  • Use of a long-acting bronchodilator during the 12 hours prior to spirometry (lung function testing)
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
19 participants (actual)
Biospecimen retention
Samples without dna

Groups and cohorts

  • Children with asthma

    African American children with clinically diagnosed stable asthma

06

What researchers measure

Primary outcomes

  1. Interleukin-13 from phytohemagglutinin activated peripheral blood mononuclear cells

    Time frame: 7 months (from the start to completion of study. The blood was drawn at the one and only visit for each subject)

Secondary outcomes

  1. Lung function measured by percent predicted forced expiratory volume in the first second (FEV1%)

    Time frame: 7 months (from the start to completion of study, but FEV1% was measured at the one and only visit for each subject)

07

Study locations

1 site
  • Rush University Medical Center; Clinic: University Consultants in Allergy and Immunology
    Chicago, Illinois 60612, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 28, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00968305
Lead sponsor
Rush University Medical Center
First posted
Aug 28, 2009
Start date
Nov 2008
Primary completion
Aug 2009
Completion
Aug 2009
Last update
Aug 28, 2009

Study contacts

Byung H Yu, MD
principal investigator · Rush University Medical Center, Department of Immunology and Microbiology

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2009. You cannot join it, but the record below documents what was studied.

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