CClinicalTrials.gg
Status unknownNCT00935571Updated Jul 9, 2009

Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia

An observational study in Lung Cancer and Neoplasms, Lung, sponsored by Asan Medical Center. Status unknown at 1 site in Korea, Republic of. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-07-09.

Sponsored by Asan Medical Center · Observational

The sponsor has not verified this record recently (last verified Jul 2009), so the status shown — last known as Active, not recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
400
Ages
18 Years and older
Sex
All
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Study summary

The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.

Read the detailed description

Thoracotomy is one of the most painful surgical incisions. It has been shown that 5-80% of patients still suffer from thoracic pain 2-3 months after surgery and the international association for the study of pain (IASP) defines postthoracotomy pain syndrome (PTTS)as pain that recurs or persists at least 2 months after surgical procedure. Previous reports have shown that the incidence of PTTS varies according to preoperative pain, pain intensity, sex, and types of procedure. However, little is known about the effect of the type of anesthesia to postthoracotomy pain.

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Conditions studied

  • Lung Cancer
  • Neoplasms, Lung

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In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,558 are open to participants now.

This study's planned enrollment of 400 is above the median of 189 across 1,512 observational studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Asan Medical Center is the lead sponsor of 562 studies on the registry; 71 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients scheduled to undergo elective thoracotomy of lung surgery

Inclusion criteria

  • patients undergo elective thoracotomy of lung surgery

Exclusion criteria

Exclusion Criteria:

  • emergency operation age under 18 years patients with unstable hemodynamics
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
400 participants (estimated)

Groups and cohorts

  • Group I, Group II

    Group I: anesthetized with TIVA (Propofol + Remifentanil) Group II: anesthetized with inhalation (sevoflurane)

    Drug: propofol, remifentanil, sevoflurane

Interventions

  • Drugpropofol, remifentanil, sevoflurane

    Propofol: using target controlled infusion (TCI); 1-3ug/ml remifentanil: using TCI by 5-20 ng/ml sevoflurane: 2-3volume% (1-2 MAC)

    Also known as: diprivan, ultiva

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What researchers measure

Primary outcomes

  1. Incidence of pain

    Time frame: 3 and 6 months later after operation

Secondary outcomes

  1. pain characters

    Time frame: 3 and 6 months later after operation

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Study locations

1 site
  • Department of Anesthesiology and Pain Medicine, University of Ulsan College of Medicine, Asan Medical Center
    Seoul, 138-736, Korea, Republic of
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References and documents

Publications

  • Gotoda Y, Kambara N, Sakai T, Kishi Y, Kodama K, Koyama T. The morbidity, time course and predictive factors for persistent post-thoracotomy pain. Eur J Pain. 2001;5(1):89-96. doi: 10.1053/eujp.2001.0225. PubMed 11394926 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 9, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00935571
Lead sponsor
Asan Medical Center
First posted
Jul 9, 2009
Start date
Oct 2007
Primary completion
Jun 2009 (estimated)
Completion
Sep 2009 (estimated)
Last update
Jul 9, 2009

Study contacts

In Cheol Choi, MD, PhD
study chair · Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jul 2009. You cannot join it, but the record below documents what was studied.

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