An observational study in Breast Cancer, sponsored by Queen Mary University of London. Status unknown at 18 sites in United Kingdom. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-08-12.
Sponsored by Queen Mary University of London · Observational
RATIONALE: Studying genes in samples of blood and/or tumor tissue from patients with cancer may help doctors identify biomarkers related to cancer.
PURPOSE: This research study is looking at blood and/or tumor tissue samples from patients with ductal carcinoma in situ and blood samples from healthy volunteers.
OBJECTIVES:
Primary
Secondary
OUTLINE: This is a multicenter study.
All participants complete a questionnaire to collect their family history, a brief medical history, and epidemiological data.
Patients undergo collection of blood and/or tumor tissue samples; DNA is extracted for genotyping, comparison of allele and genotype frequencies (polymorphisms), genetic profiling, DNA analysis, and protein analysis. Histopathology reports are also collected. Healthy volunteers undergo collection of blood samples.
PROJECTED ACCRUAL: A minimum of 3,000 patients and 3,000 controls will be accrued for this study.
12,815 studies on the registry are indexed under Breast Neoplasms; 2,920 are open to participants now.
This study's planned enrollment of 6,000 is above the median of 184 across 2,711 observational studies indexed under Breast Neoplasms.
Browse Breast Neoplasms studies →Queen Mary University of London is the lead sponsor of 253 studies on the registry; 59 are open to participants now.
Counted across the registry records on this site, refreshed daily.
DISEASE CHARACTERISTICS:
Prior or current diagnosis of pure ductal carcinoma in situ (DCIS)
Healthy age- and ethnicity-matched controls
PATIENT CHARACTERISTICS:
PRIOR CONCURRENT THERAPY:
Collection of blood and/or tumor tissue
Frequency of genetic variants that predispose women to develop ductal carcinoma in situ (DCIS)
Effect of these variants on tumor risk
Benefit of testing for these variants
Analysis of acquired genetic changes within DCIS
This study is status unknown, as verified in Jul 2009. You cannot join it, but the record below documents what was studied.
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