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CompletedNCT00915707Updated Sep 5, 2013

Pathways Linking Reduced Sleep Duration and Quality to Obesity Risk

An interventional study of Baseline and Sleep restriction in Obesity and Diabetes, sponsored by University of Chicago. Completed at 1 site in United States. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-09-05.

Sponsored by University of Chicago · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
23
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
01

Study summary

This study is designed to study the pathways through which short sleep duration or poor sleep quality can lead to an increased risk of developing diabetes and obesity.

02

Conditions studied

  • Obesity
  • Diabetes

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Keywords

  • obesity
  • diabetes, risk
  • obesity, diabetes risk related to sleep
03

In context

Obesity

6,296 studies on the registry are indexed under Obesity; 1,692 are open to participants now.

This study's enrollment of 23 is below the median of 78 across 4,878 interventional studies indexed under Obesity.

Browse Obesity studies →

Lead sponsor

University of Chicago is the lead sponsor of 907 studies on the registry; 182 are open to participants now.

Of its 99 completed or terminated interventional studies of FDA-regulated products, 68 (69%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Normal weight
  • Healthy
  • Normal sleep times

Exclusion criteria

Exclusion Criteria:

  • Sleep disorders
  • Overweight
  • Diabetes
  • Other health conditions
  • Excessive caffeine and alcohol intake
  • Smoking
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Participant)
Enrollment
23 participants (actual)

Study arms

  • Experimental
    Baseline

    Subjects are tested under normal sleep conditions for carbohydrate metabolism and appetite regulation.

    Other: Baseline

  • Experimental
    Sleep restriction

    Subjects are tested under sleep restriction for carbohydrate metabolism and appetite regulation.

    Other: Sleep restriction

  • Experimental
    Reduced sleep quality

    Subjects are tested under a poor sleep quality condition for carbohydrate metabolism and appetite regulation.

    Other: Reduced Sleep Quality

Interventions

  • OtherBaseline

    Subjects are allowed time in bed for sleep as their usual time at home.

  • OtherSleep restriction

    Subjects sleep is reduced to 4.5 hours in bed for 4 nights.

  • OtherReduced Sleep Quality

    Subjects sleep quality is reduced for 4 nights.

06

What researchers measure

Primary outcomes

  1. Disposition Index reflecting Diabetes Risk as a result of decreased sleep duration and/or quality.

    Time frame: 3 months

07

Study locations

1 site
  • The University of Chicago
    Chicago, Illinois 60637, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 5, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00915707
Lead sponsor
University of Chicago
Responsible party
Sponsor
First posted
Jun 8, 2009
Start date
Jan 2007
Primary completion
Jul 2012
Completion
Jul 2012
Last update
Sep 5, 2013

Study contacts

Esra Tasali, MD
principal investigator · University of Chicago

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.

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