Magnetoencephalographic (MEG) Correlates of Negative Symptoms in Patients Suffering From Schizophrenia and Their Influence by Add-on Treatments

schizophrenia patients and healthy subjects between the ages 18-65

Inclusion Criteria:

• Study Group (Schizophrenia Patients) Inclusion Criteria
• Patients between the ages of 18-65 (male and female), Diagnosed in the past as suffering from schizophrenia. The diagnosis will be reaffirmed according to ICD criteria.
• Right hand dominant.
• Scores in PANSS negative questionnaire above 21 and positive symptom less than 24.
• Gave informed consent for participation in the study.
• Stable on the same antipsychotic medication for at least a month prior to entering the study Control Group (healthy Subjects)

Inclusion criteria:

• Healthy man and woman
• Ages 18-65
• Right handed

Exclusion Criteria:

• Study Group (Schizophrenia Patients) (To prevent MEG artifacts by non relevant electric interference or brain conditions)
• History of epilepsy, seizure, or hot spasm, sever head injuries.
• History of metal in the head (outside the mouth space).
• History of surgery including metal implant or history of metal particles in the eye, pacemaker, or any other medical pump.
• History of migraines.
• History of drug or alcohol abuse during the last year. Inability to achieve satisfying level of communication with the subject Control Group (healthy Subjects)
• History of psychiatric diagnosis
• Drug or alcohol addiction in the year prior to the study
• History of epilepsy, seizure, or hot spasm.
• History of head injuries.
• History of metal in the head (outside the mouth space).
• History of surgery including metal implant or history of metal particles in the eye, pacemaker, or any other medical pump.
• History of migraines.
• Use of psychotropic medication