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CompletedNCT00892905Updated Jun 10, 2026

Comparing Point of Care Clotting Tests in the OR Versus Standard Laboratory Clotting Tests

An observational study in Coronary Artery Bypass Grafting, sponsored by McMaster University. Completed at 1 site in Canada. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-06-10.

Sponsored by McMaster University · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
20
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The purpose of this study is determine the agreement of point of care (POC) clotting tests (INR and aPTT) by the POC device by Hemochron Jr versus standard laboratory clotting tests (INR and aPTT) in patients undergoing elective cardiac surgery.

Read the detailed description

The study is a correlation between POC Hemochron Jr INR and aPTT with the standard.

02

Conditions studied

  • Coronary Artery Bypass Grafting

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Keywords

  • coagulation
  • INR
  • aPTT
  • point of care
  • laboratory
  • CABG
  • surgery
03

In context

Thrombosis

1,506 studies on the registry are indexed under Thrombosis; 238 are open to participants now.

This study's enrollment of 20 is below the median of 213 across 586 observational studies indexed under Thrombosis.

Browse Thrombosis studies →

Lead sponsor

McMaster University is the lead sponsor of 720 studies on the registry; 124 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patient undergoing elective on pump CABG

Inclusion criteria

  • did not receive anticoagulants or clopidogrel within 5 days preoperatively

Exclusion criteria

Exclusion Criteria:

  • history of coagulopathy
  • heparin resistance
  • receiving heparin or warfarin
  • hepatic or renal dysfunction
  • pregnancy
  • urgent or emergency cases
05

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
20 participants (actual)
Patient registry
No

Groups and cohorts

  • POC INR and APTT Hemochron

    Adult patients undergoing elective on pump coronary artery bypass grafting surgery who have not received anticoagulants or clopidogrel within 5 days preoperatively.

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What researchers measure

Primary outcomes

  1. Correlation between pre cardiopulmonary bypass (CPB) and post CPB POC INR and PTT with standard laboratory INR and PTT

    Time frame: 2 months

07

Study locations

1 site
  • Hamilton General Hospital
    Hamilton, Ontario L8L 2X2, Canada
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00892905
Lead sponsor
McMaster University
Collaborators
St. Joseph's Healthcare Hamilton
Responsible party
Sponsor
First posted
May 5, 2009
Start date
Jan 2008
Primary completion
Jan 2011
Completion
Jan 2011
Last update
Jun 10, 2026

Study contacts

Summer Syed, MD
principal investigator · Hamilton Health Sciences Corporation

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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