An observational study in Chronic Obstructive Pulmonary Disease and Lung Cancer, sponsored by KU Leuven. Status unknown at 1 site in Belgium. Open to participants aged 25 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-09-04.
Sponsored by KU Leuven · Observational
A biobank of Serum, plasma, DNA samples together with clinical information including specific questionnaires, complete pulmonary function and chest CT-scan, is prospectively collected in patients seen at the investigators' clinical service.
The objective is to study candidate gene pathways in COPD and or lung cancer and to associate them with the clinical characteristics and phenotypes of COPD/emphysema and lung cancer.
In subgroups of well characterised patients, other biological materials are also collected (lung tissue biopsies, peripheral blood mononuclear cells).
All patients with a smoking history of at least 15 pack years, an minimal age of 50 years and an recent available CT scan are enrolled.
All subjects with a diagnosis of lung cancer are also collected (irrespective of age and smoking behavior).
In addition the investigators collect:
In specific subgroups the investigators also collect:
7,243 studies on the registry are indexed under Lung Neoplasms; 1,558 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 189 across 1,512 observational studies indexed under Lung Neoplasms.
Browse Lung Neoplasms studies →KU Leuven is the lead sponsor of 358 studies on the registry; 62 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with Chronic Obstructive Pulmonary Disease and smoking controls.
Inclusion Criteria for smokers:
Exclusion Criteria for smokers:
Inclusion Criteria for lung cancer patients:
Exclusion Criteria for lung cancer patients
Smokers without lung cancer and without COPD
Smokers with COPD but without lung cancer
smokers - never smokers with lung cancer
Serological, cytological, histological and genetic analysis of biomarkers or genes which are involved in the pathogenesis of COPD/Emphysema/Lungcancer.
All cases are prospectively collected in University hospital Leuven, Belgium. Of enrolled subjects data are collected at 0,1,3 and 6 years interval
Time frame: 0-1-3-6 years
This study is status unknown, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.
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KU Leuven