An observational study in Colon Cancer and Rectal Cancer, sponsored by North Texas Veterans Healthcare System. Completed at 3 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-11-01.
Sponsored by North Texas Veterans Healthcare System · Observational
This is a clinical research study to look at the incidence of proteinuria (a condition in which urine contains an abnormal amount of protein) caused by shortened infusions (given into the vein over 10 or 15 minutes) of bevacizumab (a medication prescribed for colon, lung, or breast cancer). There are currently no published studies or clinical data looking at how safe shortened infusions of bevacizumab are in relationship to the side effect of proteinuria. We hypothesis that shortened infusions of bevacizumab will result in an increased risk for proteinuria compared to the standard infusions of this agent.
234 studies on the registry are indexed under Proteinuria; 43 are open to participants now.
This study's enrollment of 106 is below the median of 125 across 53 observational studies indexed under Proteinuria.
Browse Proteinuria studies →North Texas Veterans Healthcare System is the lead sponsor of 31 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
106 patients receiving bevacizumab doses of \< 10 mg/kg at a rate of 0.5 mg/kg/min in hematology/oncology outpatient clinic. Most of the patients are likely to have advanced stage colon or rectal cancer.
Exclusion Criteria:
Shortened infusions of bevacizumab
To evaluate the effect of shortened infusions (0.5 mg/kg/min) of bevacizumab on the incidence of proteinuria.
Time frame: 3-6 months
To evaluate the time (number of days) to the incidence of proteinuria with shortened infusions of bevacizumab AND to evaluate the effect of controlled versus uncontrolled hypertension and the incidence of proteinuria.
Time frame: 3-6 months
This study is completed, as verified in Feb 2009. You cannot join it, but the record below documents what was studied.
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North Texas Veterans Healthcare System