An interventional study of Mustard (dijon) and Placebo in Healthy, sponsored by University of Copenhagen. Completed at 1 site in Denmark. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2009-02-11.
Sponsored by University of Copenhagen · Not applicable, Interventional, and Prevention
The objective of this study is to examine whether a specific spice is capable of affecting energy metabolism.
Since chili and other spices have been shown to increase energy expenditure and in some cases also affect energy intake/appetite compared to placebo, the investigators expect that the specific spice may actually increase energy expenditure and potentially also decrease appetite - although not to a large degree.
Several pungent food ingredients, such as chili, and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food, since a few studies have suggested an effect of bioactive ingredients on appetite/energy intake. We expect to see some small effects on these parameters.
University of Copenhagen is the lead sponsor of 465 studies on the registry; 63 are open to participants now.
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Exclusion Criteria:
Mustard
Dietary Supplement: Mustard (dijon)
Placebo
Dietary Supplement: Placebo
Drug pages: Mechlorethamine · Mustard Gas
The specific spice added to a brunch meal
Placebo added to a brunch meal
Energy expenditure (resting)/Meal-induced thermogenesis
Time frame: November 2008
VAS-scores for different appetite parameters (incl. satiety, hunger, fullness, prospective food intake, well-being, thirst etc.)
Time frame: November 2008
Blood pressure
Time frame: November 2008
Heart rate
Time frame: November 2008
Substrate oxidation (fat and carbohydrate)
Time frame: November 2008
This study is completed, as verified in Feb 2009. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Mechlorethamine · Mustard Gas