An interventional study of Training in Transposition of Great Vessels, sponsored by Hannover Medical School. Completed at 1 site in Germany. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2012-03-09.
Sponsored by Hannover Medical School · Not applicable, Interventional, and Diagnostic
In transposition patients after atrial switch operation, the morphological right ventricle serves as the systemic ventricle. These patients often develop signs of heart failure. It is not known, whether physical training can safely be recommended in these patients- like heart failure guidelines recommend training in patients with normal anatomy. Furthermore it is not known, whether these TGA-patients benefit from training with respect to cardiopulmonary exercise capacity.
This is a randomized, controlled, prospective trial on the safety of physical training in TGA patients after atrial switch operation.
In transposition patients after atrial switch operation, the morphological right ventricle serves as the systemic ventricle. These patients often develop signs of heart failure. It is not known, whether physical training can safely be recommended in these patients- like heart failure guidelines recommend training in patients with normal anatomy. Furthermore it is not known, whether these TGA-patients benefit from training with respect to cardiopulmonary exercise capacity.
Primary endpoints are Systemic Ventricle Ejection Fraction and Volumes, Exercise Capacity.
Secondary endpoints are Echo Diastolic Function, as well as laboratory markers of heart failure.
45 studies on the registry are indexed under Transposition of Great Vessels; 9 are open to participants now.
This study's planned enrollment of 48 is below the median of 56 across 21 interventional studies indexed under Transposition of Great Vessels.
Browse Transposition of Great Vessels studies →Hannover Medical School is the lead sponsor of 198 studies on the registry; 24 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Ergometer Training
Behavioral: Training
Counseling
Controlled home ergometer training
Also known as: ergometer, physical exercise
Cardiac MRI Right Ventricular Ejection Fraction
Time frame: 6 and 12 months
Cardiopulmonary exercise capacity
Time frame: 6 and 12 months
laboratory markers of heart failure
Time frame: 6 and 12 months
Diastolic RV and LV function
Time frame: 6 and 12 months
Right ventricular volumes
Time frame: 6 and 12 months
Right ventricular mass
Time frame: 6 and 12 months
NYHA-class
Time frame: 6 and 12 months
quality of life questionnaire
Time frame: 6 and 12 months
This study is completed, as verified in Jul 2011. You cannot join it, but the record below documents what was studied.
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Transposition of Great Vessels→
Hannover Medical School