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CompletedNCT00833144Updated Dec 13, 2013

Bedside Ultrasound Identifies Congestive Heart Failure

An observational study in Heart Failure and Dyspnea, sponsored by Emory University. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-12-13.

Sponsored by Emory University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
375
Ages
18 Years and older
Sex
All
01

Study summary

Patients often arrive to the Emergency Department with the chief complaint of shortness of breath. The cause of the shortness of breath may be due to many things, such as pneumonia, emphysema, a heart attack, heart failure, and others. It is often very difficult for the physician to determine the cause of the shortness of breath in the first two hours in the Emergency Department. This ambiguity makes treating the patient very difficult. Although a patient could benefit from treatment upon arrival, the emergent treatment of the condition must wait until a final diagnosis is made.

Recently, emergency physicians have been using portable ultrasound at the patient's bedside to diagnose numerous conditions, including trauma, blood clots, kidney stones, etc. Recent research suggests that heart failure, one of the causes of shortness of breath, may be diagnosed within 5 minutes or less using ultrasound. Most of these studies come from the intensive care and cardiology. However, no research has yet been performed to determine if emergency physicians can effectively use ultrasound to quickly diagnose and treat heart failure within the first few minutes of a patient's arrival to the emergency department. The hypothesis of this study is to evaluate the ability of residents in emergency medicine to use ultrasound to diagnose patients in heart failure who presented with the chief complaint of shortness of breath. The final diagnosis of the patient upon discharge from the hospital will be compared to the preliminary diagnosis based on the portable ultrasound findings.

02

Conditions studied

  • Heart Failure
  • Dyspnea

Keywords

  • heart failure
  • dyspnea
  • ultrasound
03

In context

Dyspnea

656 studies on the registry are indexed under Dyspnea; 153 are open to participants now.

This study's enrollment of 375 is above the median of 122 across 204 observational studies indexed under Dyspnea.

Browse Dyspnea studies →

Lead sponsor

Emory University is the lead sponsor of 1,386 studies on the registry; 236 are open to participants now.

Of its 229 completed or terminated interventional studies of FDA-regulated products, 174 (76%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients presenting to the Emergency Care Center with the chief complaint of shortness of breath or dyspnea will be eligible for the study.

Inclusion criteria

  • age > 18
  • presenting complaint of shortness of breath or dyspnea

Exclusion criteria

Exclusion Criteria:

  • prisoners
  • pregnant women
  • shortness of breath clearly secondary to another diagnosis (i.e. trauma)
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
375 participants (actual)
Patient registry
No

Groups and cohorts

  • 1

    Congestive Heart Failure

  • 2

    Patients without congestive heart failure

06

What researchers measure

Primary outcomes

  1. sensitivity and specificity of the ultrasound lung rockets to predict congestive heart failure

    Time frame: One year

Secondary outcomes

  1. comparison of the BNP with the thoracic ultrasound findings

    Time frame: One year

07

Study locations

1 site
  • Grady Memorial Hospital
    Atlanta, Georgia 30303, United States
08

References and documents

Publications

  • Agricola E, Bove T, Oppizzi M, Marino G, Zangrillo A, Margonato A, Picano E. "Ultrasound comet-tail images": a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water. Chest. 2005 May;127(5):1690-5. doi: 10.1378/chest.127.5.1690. PubMed 15888847 ↗
  • Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, Picano E. Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol. 2004 May 15;93(10):1265-70. doi: 10.1016/j.amjcard.2004.02.012. PubMed 15135701 ↗
  • Lichtenstein D, Meziere G. A lung ultrasound sign allowing bedside distinction between pulmonary edema and COPD: the comet-tail artifact. Intensive Care Med. 1998 Dec;24(12):1331-4. doi: 10.1007/s001340050771. PubMed 9885889 ↗
  • Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AH, Clopton P, Steg PG, Westheim A, Knudsen CW, Perez A, Kazanegra R, Herrmann HC, McCullough PA; Breathing Not Properly Multinational Study Investigators. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med. 2002 Jul 18;347(3):161-7. doi: 10.1056/NEJMoa020233. PubMed 12124404 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 13, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00833144
Lead sponsor
Emory University
Responsible party
Sierra Beck, MD, RDMS (Assistant Professor, Emory University) — Principal investigator
First posted
Jan 30, 2009
Start date
Feb 2009
Primary completion
Feb 2010
Completion
Feb 2011
Last update
Dec 13, 2013

Study contacts

William Manson, MD
principal investigator · Emory University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2013. You cannot join it, but the record below documents what was studied.

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