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CompletedNCT00825461Updated Jan 9, 2018

Ghrelin With Anorexia Nervosa

An observational study in Anorexia Nervosa, sponsored by Maastricht University Medical Center. Completed at 1 site in Netherlands. Open to female participants aged 12 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-01-09.

Sponsored by Maastricht University Medical Center · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
20
Ages
12 Years to 35 Years
Sex
Female
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Study summary

The PICOWO research group in corporation with the University of Amsterdam (Artificial Intelligence) has developed a computer simulationmodel of eating disorders (Bosse, Delfos, Jonker \& Treur, 2003). In a running Phd project we want to add ghrelin to the model. The idea for this current research is to collect clinical information about the functioning and (patho)physiology of ghrelin in patients with AN, so we can extend the simulation.

Read the detailed description

Eating disorders are in need of new perspectives. A better understanding of the appetite in patients with eating disorders, especially Anorexia Nervosa, could be investigated by the levels of ghrelin in patients with and without tube feeding.

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Conditions studied

  • Anorexia Nervosa

Keywords

  • Anorexia Nervosa
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In context

Anorexia

411 studies on the registry are indexed under Anorexia; 67 are open to participants now.

This study's enrollment of 20 is below the median of 65 across 104 observational studies indexed under Anorexia.

Browse Anorexia studies →

Lead sponsor

Maastricht University Medical Center is the lead sponsor of 835 studies on the registry; 122 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
12 Years to 35 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Studypopulation: Patiënts: all female, non -age coupled. Subgroup patients without tube feeding, with tube feeding and a healthy matched control group.

Control group: healthy volunteers of the University of Maastricht.

Inclusion criteria

  • Studypopulation: Patiënts: all female, non -age coupled.
  • Subgroup patients without tube feeding, with tube feeding and a healthy matched control group.
  • Control group: healty volunteers of the University of Maastricht.

Exclusion criteria

Exclusion Criteria:

  • Patients with a history of eating disorder different than AN or a psychiatric history.
  • Control group: no history of eating disorders or other psychiatric disabilities. Normal physical examination, ecg, laboratorium (blood cells, liver, kidneys)
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
20 participants (actual)
Biospecimen retention
Samples with dna

Groups and cohorts

  • 1

    Anorexia with tube feeding

  • 2

    Anorexia without tube feeding

  • 3

    Control

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What researchers measure

Primary outcomes

  1. Concentration of ghrelin in blood.

    Time frame: 1 morning

07

Study locations

1 site
  • University Hospital Maastricht
    Maastricht, Limburg 6202 AZ, Netherlands
08

References and documents

Publications

  • Bosse, T.; Delfos., M.F.; Jonker, C.M. & Treur, J. (2003). Reasoning about adaptive Dynamical Systems in the Analysis of eating Regulation Disorders. N.J. Mahwah. Proceedings of the 25th Annual Conference of the Cognitive Science Society. Lawrence Erlbaum Associates Inc.
  • Both, F. & Delfos, M.F. (in preparation). The role of ghrelin in eating disorders, a review.
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 9, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00825461
Lead sponsor
Maastricht University Medical Center
Responsible party
Sponsor
First posted
Jan 21, 2009
Start date
Mar 2009
Primary completion
Dec 2011
Completion
Dec 31, 2012
Last update
Jan 9, 2018

Study contacts

Martine F Delfos, Dr
principal investigator · PICOWO Utrecht

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2009. You cannot join it, but the record below documents what was studied.

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