CClinicalTrials.gg
Status unknownNCT00782782Updated Oct 31, 2008

Vascular Sensitivity to Adrenergic Agonists in Patients With CHF and in Healthy Subjects

An observational study in Congestive Heart Failure, sponsored by Hadassah Medical Organization. Status unknown at 1 site in Israel. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-10-31.

Sponsored by Hadassah Medical Organization · Observational

The sponsor has not verified this record recently (last verified Oct 2008), so the status shown — last known as Active, not recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
80
Ages
18 Years to 70 Years
Sex
All
01

Study summary

Congestive Heart failure (CHF) is asociated with changes in cardiac function and vascular responses. The aim of this study is to characterize these differences. Our hypothesis is, that there are differences in vascular responses between healthy subjects and patients with CHF.

02

Conditions studied

  • Congestive Heart Failure

Browse trials for

03

In context

Heart Failure

5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.

This study's planned enrollment of 80 is below the median of 200 across 1,679 observational studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

Hadassah Medical Organization is the lead sponsor of 659 studies on the registry; 54 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with congestive heart failure NYHA I-II and healthy subjects

Inclusion criteria

  • Patients with congestive heart failure NYHA I-II
  • Stable clinical condition

Exclusion criteria

Exclusion Criteria:

  • Resting systolic blood pressure \< 100
  • Resting heart rate \< 50
  • Hypersensitivity to dexmedetomidine, phenylephrine, isoproterenol, terbutaline
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
80 participants (estimated)
Biospecimen retention
Samples without dna
06

What researchers measure

Primary outcomes

  1. vascular sensitivity (ED50) and response (Emax) to dexmedetomidine, phenylephrine, isoproterenol and terbutaline

    Time frame: 3 weeks

07

Study locations

1 site
  • Hadassah University Hospital
    Jerusalem, 92110, Israel
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 31, 2008, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00782782
Lead sponsor
Hadassah Medical Organization
First posted
Oct 31, 2008
Start date
Aug 2008
Primary completion
Dec 2009 (estimated)
Completion
Dec 2011 (estimated)
Last update
Oct 31, 2008

Study contacts

Mordechai Muszkat
principal investigator · Hadassah University Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Oct 2008. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion