An interventional study of Sugar-sweetened soft drink and Aspartame-sweetened soft drink in Obesity and Diet, sponsored by Aarhus University Hospital. Completed at 1 site in Denmark. Open to participants aged 20 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-10-22.
Sponsored by Aarhus University Hospital · Not applicable and Interventional
Compared to solid foods, the nutritional energy of drinks may bypass the appetite regulation leading to obesity development. Although drinks sweetened with aspartame are available the anticipated positive effect of these drinks on obesity development has not been convincing. However, the mechanisms linking drinks intake to obesity are yet to be clarified.
The investigators aim is to investigate the short-term effects of soft drinks (sugar-sweetened and artificially sweetened (aspartame)), milk and water on the concentration of circulating appetite-regulating hormones, the subjective sensations of hunger and satiety (measured by visual analogue scales) and energy intake. The study is a crossover, intervention trial with 24 overweight, healthy volunteers. The subjects will be tested on four separate days for four hours. Each test day a preload drink (sugar-sweetened soft drink, aspartame-sweetened soft drink, semi-skimmed milk or water) is served.
The investigators expect to clarify the mechanisms linking drinking habits to obesity development and provide scientifically based nutritional guidelines.
6,570 studies on the registry are indexed under Obesity; 1,718 are open to participants now.
This study's enrollment of 24 is below the median of 77 across 5,084 interventional studies indexed under Obesity.
Browse Obesity studies →Aarhus University Hospital is the lead sponsor of 295 studies on the registry; 81 are open to participants now.
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Exclusion Criteria:
54g sugar/L, 180kJ/100mL
Other: Sugar-sweetened soft drink
1.5kJ/100mL
Other: Aspartame-sweetened soft drink
202kJ/100mL
Other: Semi-skimmed milk
0kJ/100mL
Other: Water
500mL as a preload drink
500mL as a preload drink
500mL as a preload drink
500mL as a preload drink
Visual Analogue Scale
Time frame: Four hours
Appetite-regulating hormones, Glucose, Insulin; Energy intake
Time frame: Four hours
This study is completed, as verified in Aug 2008. You cannot join it, but the record below documents what was studied.
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