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CompletedNCT00754611Updated Oct 28, 2019

The Evolution and Management of Migraine Recurrence Beyond 24 Hours

An observational study in Migraine, sponsored by Rowan University. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-10-28.

Sponsored by Rowan University · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

What is the course of migraine headache recurrence, how is it managed, what characteristics are associated with it, and how does it influence patient satisfaction with treatment?

02

Conditions studied

03

In context

Migraine Disorders

1,528 studies on the registry are indexed under Migraine Disorders; 299 are open to participants now.

This study's enrollment of 100 is below the median of 130 across 299 observational studies indexed under Migraine Disorders.

Browse Migraine Disorders studies →

Lead sponsor

Rowan University is the lead sponsor of 25 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients at the University Headache Center, aged 18 or older, with a diagnosis of migraine with and/or without aura as defined by ICHD-II criteria

Inclusion criteria

  • Female and male patients at University Headache Center with > 6 month diagnosis of migraine with and/or without aura (ICHD-II)
  • Greater than or equal to 18 years old

Exclusion criteria

Exclusion Criteria:

  • Greater than 15 days/month total headache days
  • Analgesic use greater than 15 days/month (other than aspirin less than or equal to 325mg/d)
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
100 participants (actual)
06

What researchers measure

Primary outcomes

  1. Primary efficacy outcomes will be sustained pain free response between 4 and 72 hours after initial abortive medication dosing (lack of recurrence over 72 hours)

    Time frame: 4 to 72 hours

Secondary outcomes

  1. Pain response and pain free data

    Time frame: 30 minutes, 1,2,4,24,48,and 72 hours

  2. Rate of recurrence, time of recurrence, time to re-dosing

    Time frame: 72 hours

  3. Rate of recurrence among multiple attacks per subject

    Time frame: 72 hours

07

Study locations

1 site
  • University of Medicine and Dentistry of New Jersey
    Stratford, New Jersey 08084, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 28, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00754611
Lead sponsor
Rowan University
Collaborators
Endo Pharmaceuticals
Responsible party
Sponsor
First posted
Sep 18, 2008
Start date
Dec 2008
Primary completion
Dec 2010
Completion
Dec 2010
Last update
Oct 28, 2019

Study contacts

Loretta Mueller, DO
principal investigator · Rutgers, The State University of New Jersey

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2019. You cannot join it, but the record below documents what was studied.

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