A Phase 4 interventional study of losartan and amlodipine in Ischemic Stroke, sponsored by Taipei Veterans General Hospital, Taiwan. Completed. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2013-10-23.
Sponsored by Taipei Veterans General Hospital, Taiwan · Phase 4, Interventional, and Treatment
To compare the effect of losartan vs amlodipine-based antihypertensive therapy on atherosclerotic inflammatory markers and cerebrovascular regulation in Ischemic stroke patients.
7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.
This study's enrollment of 40 is below the median of 50 across 5,369 interventional studies indexed under Stroke.
Browse Stroke studies →Taipei Veterans General Hospital, Taiwan is the lead sponsor of 325 studies on the registry; 72 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Losartan 50mg qd for 30 weeks, if blood pressure \> 140/90, or mean arterial Bp ≧ 15% of baseline, then add on diuretics.
Drug: losartan
Amlodipine 5 mg q.d for 30 weeks, if blood pressure \> 140/90, or mean arterial Bp ≧ 15% of baseline, then add on diuretics.
Drug: amlodipine
losartan 50mg qd for 30 weeks.
Also known as: losartan potassium, COZAAR®, MK0954
amlodipine 5 mg q.d for 30 weeks.
Also known as: Norvasc
MCAFV and TCD for measuring cerebral autoregulatory indices at week 0, week 6, week 18 and week 30.
Time frame: At week 0, week 6, week 18 and week 30.
No study locations are listed for this record.
This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.
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Taipei Veterans General Hospital, Taiwan